Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS20062394HPVENSG00000133742.14protein_codingCA1NoNo759P00915
TVIS44045853HTLV-1ENSG00000133742.14protein_codingCA1NoNo759P00915
TVIS44045852HTLV-1ENSG00000133742.14protein_codingCA1NoNo759P00915
TCGA Plot Options
Drug Information
GeneCA1
DrugBank IDDB01194
Drug NameBrinzolamide
Target IDBE0000267
UniProt IDP00915
Regulation Typeinhibitor
PubMed IDs14684332; 11224713
CitationsWinum JY, Casini A, Mincione F, Starnotti M, Montero JL, Scozzafava A, Supuran CT: Carbonic anhydrase inhibitors: N-(p-sulfamoylphenyl)-alpha-D-glycopyranosylamines as topically acting antiglaucoma agents in hypertensive rabbits. Bioorg Med Chem Lett. 2004 Jan 5;14(1):225-9.@@Herkel U, Pfeiffer N: Update on topical carbonic anhydrase inhibitors. Curr Opin Ophthalmol. 2001 Apr;12(2):88-93.
GroupsApproved
Direct ClassificationThienothiazines
SMILESCCN[C@H]1CN(CCCOC)S(=O)(=O)C2=C1C=C(S2)S(N)(=O)=O
Pathways
PharmGKBPA164744929
ChEMBLCHEMBL220491