| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10035966 | HBV | ENSG00000085563.15 | protein_coding | ABCB1 | Yes | No | 5243 | A4D1D2 P08183 |
| TVIS30067436 | HIV | ENSG00000085563.15 | protein_coding | ABCB1 | Yes | No | 5243 | A4D1D2 P08183 |
| TVIS20061554 | HPV | ENSG00000085563.15 | protein_coding | ABCB1 | Yes | No | 5243 | A4D1D2 P08183 |
| TVIS20061565 | HPV | ENSG00000085563.15 | protein_coding | ABCB1 | Yes | No | 5243 | A4D1D2 P08183 |
| TVIS20061861 | HPV | ENSG00000085563.15 | protein_coding | ABCB1 | Yes | No | 5243 | A4D1D2 P08183 |
| TVIS44008599 | HTLV-1 | ENSG00000085563.15 | protein_coding | ABCB1 | Yes | No | 5243 | A4D1D2 P08183 |
| TVIS44039492 | HTLV-1 | ENSG00000085563.15 | protein_coding | ABCB1 | Yes | No | 5243 | A4D1D2 P08183 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | ABCB1 |
|---|---|
| DrugBank ID | DB14061 |
| Drug Name | Hycanthone |
| Target ID | BE0001032 |
| UniProt ID | P08183 |
| Regulation Type | inhibitor |
| PubMed IDs | 21235729; 29145976 |
| Citations | Palmeira A, Rodrigues F, Sousa E, Pinto M, Vasconcelos MH, Fernandes MX: New uses for old drugs: pharmacophore-based screening for the discovery of P-glycoprotein inhibitors. Chem Biol Drug Des. 2011 Jul;78(1):57-72. doi: 10.1111/j.1747-0285.2011.01089.x. Epub 2011 Mar 29.@@Genovese I, Ilari A, Assaraf YG, Fazi F, Colotti G: Not only P-glycoprotein: Amplification of the ABCB1-containing chromosome region 7q21 confers multidrug resistance upon cancer cells by coordinated overexpression of an assortment of resistance-related proteins. Drug Resist Updat. 2017 May;32:23-46. doi: 10.1016/j.drup.2017.10.003. Epub 2017 Oct 16. |
| Groups | Experimental |
| Direct Classification | |
| SMILES | CCN(CC)CCNC1=C2C(=O)C3=CC=CC=C3SC2=C(CO)C=C1 |
| Pathways | |
| PharmGKB | |
| ChEMBL | CHEMBL22077 |
