| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10035966 | HBV | ENSG00000085563.15 | protein_coding | ABCB1 | Yes | No | 5243 | A4D1D2 P08183 |
| TVIS30067436 | HIV | ENSG00000085563.15 | protein_coding | ABCB1 | Yes | No | 5243 | A4D1D2 P08183 |
| TVIS20061554 | HPV | ENSG00000085563.15 | protein_coding | ABCB1 | Yes | No | 5243 | A4D1D2 P08183 |
| TVIS20061565 | HPV | ENSG00000085563.15 | protein_coding | ABCB1 | Yes | No | 5243 | A4D1D2 P08183 |
| TVIS20061861 | HPV | ENSG00000085563.15 | protein_coding | ABCB1 | Yes | No | 5243 | A4D1D2 P08183 |
| TVIS44008599 | HTLV-1 | ENSG00000085563.15 | protein_coding | ABCB1 | Yes | No | 5243 | A4D1D2 P08183 |
| TVIS44039492 | HTLV-1 | ENSG00000085563.15 | protein_coding | ABCB1 | Yes | No | 5243 | A4D1D2 P08183 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | ABCB1 |
|---|---|
| DrugBank ID | DB04905 |
| Drug Name | Tesmilifene |
| Target ID | BE0001032 |
| UniProt ID | P08183 |
| Regulation Type | inducer |
| PubMed IDs | 16413681; 10755318 |
| Citations | Vincent M: Tesmilifene may enhance breast cancer chemotherapy by killing a clone of aggressive, multi-drug resistant cells through its action on the p-glycoprotein pump. Med Hypotheses. 2006;66(4):715-31. Epub 2006 Jan 18.@@Brandes LJ, Queen GM, LaBella FS: N,N-diethyl-2-[4-(phenylmethyl)phenoxy] ethanamine (DPPE) a chemopotentiating and cytoprotective agent in clinical trials: interaction with histamine at cytochrome P450 3A4 and other isozymes that metabolize antineoplastic drugs. Cancer Chemother Pharmacol. 2000;45(4):298-304. |
| Groups | Investigational |
| Direct Classification | Diphenylmethanes |
| SMILES | CCN(CC)CCOC1=CC=C(CC2=CC=CC=C2)C=C1 |
| Pathways | |
| PharmGKB | |
| ChEMBL | CHEMBL26424 |
