| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10035966 | HBV | ENSG00000085563.15 | protein_coding | ABCB1 | Yes | No | 5243 | A4D1D2 P08183 |
| TVIS30067436 | HIV | ENSG00000085563.15 | protein_coding | ABCB1 | Yes | No | 5243 | A4D1D2 P08183 |
| TVIS20061554 | HPV | ENSG00000085563.15 | protein_coding | ABCB1 | Yes | No | 5243 | A4D1D2 P08183 |
| TVIS20061565 | HPV | ENSG00000085563.15 | protein_coding | ABCB1 | Yes | No | 5243 | A4D1D2 P08183 |
| TVIS20061861 | HPV | ENSG00000085563.15 | protein_coding | ABCB1 | Yes | No | 5243 | A4D1D2 P08183 |
| TVIS44008599 | HTLV-1 | ENSG00000085563.15 | protein_coding | ABCB1 | Yes | No | 5243 | A4D1D2 P08183 |
| TVIS44039492 | HTLV-1 | ENSG00000085563.15 | protein_coding | ABCB1 | Yes | No | 5243 | A4D1D2 P08183 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | ABCB1 |
|---|---|
| DrugBank ID | DB14063 |
| Drug Name | Dexverapamil |
| Target ID | BE0001032 |
| UniProt ID | P08183 |
| Regulation Type | inhibitor |
| PubMed IDs | 16842217; 8820952; 7636539 |
| Citations | Nobili S, Landini I, Giglioni B, Mini E: Pharmacological strategies for overcoming multidrug resistance. Curr Drug Targets. 2006 Jul;7(7):861-79.@@Bates SE, Wilson WH, Fojo AT, Alvarez M, Zhan Z, Regis J, Robey R, Hose C, Monks A, Kang YK, Chabner B: Clinical reversal of multidrug resistance. Stem Cells. 1996 Jan;14(1):56-63. doi: 10.1002/stem.140056.@@Wilson WH, Jamis-Dow C, Bryant G, Balis FM, Klecker RW, Bates SE, Chabner BA, Steinberg SM, Kohler DR, Wittes RE: Phase I and pharmacokinetic study of the multidrug resistance modulator dexverapamil with EPOCH chemotherapy. J Clin Oncol. 1995 Aug;13(8):1985-94. doi: 10.1200/JCO.1995.13.8.1985. |
| Groups | Experimental |
| Direct Classification | |
| SMILES | COC1=CC=C(CCN(C)CCC[C@@](C#N)(C(C)C)C2=CC(OC)=C(OC)C=C2)C=C1OC |
| Pathways | |
| PharmGKB | |
| ChEMBL | CHEMBL197 |
