| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10019035 | HBV | ENSG00000198848.13 | protein_coding | CES1 | No | No | 1066 | P23141 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | CES1 |
|---|---|
| DrugBank ID | DB06442 |
| Drug Name | Avasimibe |
| Target ID | BE0002705 |
| UniProt ID | P23141 |
| Regulation Type | |
| PubMed IDs | 11282910; 12396226 |
| Citations | Delsing DJ, Offerman EH, van Duyvenvoorde W, van Der Boom H, de Wit EC, Gijbels MJ, van Der Laarse A, Jukema JW, Havekes LM, Princen HM: Acyl-CoA:cholesterol acyltransferase inhibitor avasimibe reduces atherosclerosis in addition to its cholesterol-lowering effect in ApoE*3-Leiden mice. Circulation. 2001 Apr 3;103(13):1778-86.@@Sudhop T, von Bergmann K: Cholesterol absorption inhibitors for the treatment of hypercholesterolaemia. Drugs. 2002;62(16):2333-47. |
| Groups | Investigational |
| Direct Classification | Aromatic monoterpenoids |
| SMILES | CC(C)C1=CC(C(C)C)=C(CC(=O)NS(=O)(=O)OC2=C(C=CC=C2C(C)C)C(C)C)C(=C1)C(C)C |
| Pathways | |
| PharmGKB | |
| ChEMBL | CHEMBL101309 |
