| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10019035 | HBV | ENSG00000198848.13 | protein_coding | CES1 | No | No | 1066 | P23141 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | CES1 |
|---|---|
| DrugBank ID | DB01452 |
| Drug Name | Diamorphine |
| Target ID | BE0002705 |
| UniProt ID | P23141 |
| Regulation Type | |
| PubMed IDs | 9311626 |
| Citations | Brzezinski MR, Spink BJ, Dean RA, Berkman CE, Cashman JR, Bosron WF: Human liver carboxylesterase hCE-1: binding specificity for cocaine, heroin, and their metabolites and analogs. Drug Metab Dispos. 1997 Sep;25(9):1089-96. |
| Groups | Approved; Illicit; Investigational |
| Direct Classification | Morphinans |
| SMILES | [H][C@@]12C=C[C@H](OC(C)=O)[C@@H]3OC4=C(OC(C)=O)C=CC5=C4[C@]13CCN(C)[C@@H]2C5 |
| Pathways | Heroin Metabolism Pathway; Heroin Action Pathway |
| PharmGKB | PA452619 |
| ChEMBL | CHEMBL459324 |
