Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS44026442HTLV-1ENSG00000012779.12protein_codingALOX5YesYes240P09917
TVIS44036453HTLV-1ENSG00000012779.12protein_codingALOX5YesYes240P09917
TVIS44046443HTLV-1ENSG00000012779.12protein_codingALOX5YesYes240P09917
TCGA Plot Options
Drug Information
GeneALOX5
DrugBank IDDB11994
Drug NameDiacerein
Target IDBE0000248
UniProt IDP09917
Regulation Typeinhibitor
PubMed IDs22449441
CitationsSingh B, Nadkarni JR, Vishwakarma RA, Bharate SB, Nivsarkar M, Anandjiwala S: The hydroalcoholic extract of Cassia alata (Linn.) leaves and its major compound rhein exhibits antiallergic activity via mast cell stabilization and lipoxygenase inhibition. J Ethnopharmacol. 2012 May 7;141(1):469-73. doi: 10.1016/j.jep.2012.03.012. Epub 2012 Mar 17.
GroupsApproved; Investigational
Direct ClassificationAnthracenecarboxylic acids
SMILESCC(=O)OC1=CC=CC2=C1C(=O)C1=C(OC(C)=O)C=C(C=C1C2=O)C(O)=O
Pathways
PharmGKB
ChEMBLCHEMBL41286