| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS44026442 | HTLV-1 | ENSG00000012779.12 | protein_coding | ALOX5 | Yes | Yes | 240 | P09917 |
| TVIS44036453 | HTLV-1 | ENSG00000012779.12 | protein_coding | ALOX5 | Yes | Yes | 240 | P09917 |
| TVIS44046443 | HTLV-1 | ENSG00000012779.12 | protein_coding | ALOX5 | Yes | Yes | 240 | P09917 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | ALOX5 |
|---|---|
| DrugBank ID | DB00471 |
| Drug Name | Montelukast |
| Target ID | BE0000248 |
| UniProt ID | P09917 |
| Regulation Type | other/unknown |
| PubMed IDs | 15474500 |
| Citations | Ramires R, Caiaffa MF, Tursi A, Haeggstrom JZ, Macchia L: Novel inhibitory effect on 5-lipoxygenase activity by the anti-asthma drug montelukast. Biochem Biophys Res Commun. 2004 Nov 12;324(2):815-21. |
| Groups | Approved |
| Direct Classification | Linear 1,3-diarylpropanoids |
| SMILES | OC(=O)CC1(CC1)CS[C@H](CCC1=CC=CC=C1C(O)(C)C)C1=CC=CC(C=CC2=NC3=C(C=CC(Cl)=C3)C=C2)=C1 |
| Pathways | |
| PharmGKB | PA450546 |
| ChEMBL | CHEMBL787 |
