| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS30086012 | HIV | ENSG00000188778.6 | protein_coding | ADRB3 | No | No | 155 | A8KAG8 P13945 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | ADRB3 |
|---|---|
| DrugBank ID | DB00368 |
| Drug Name | Norepinephrine |
| Target ID | BE0001012 |
| UniProt ID | P13945 |
| Regulation Type | agonist |
| PubMed IDs | 17139284; 17016423; 8097243; 8106131; 8105356; 9464897 |
| Citations | Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.@@Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34.@@Carpene C, Galitzky J, Collon P, Esclapez F, Dauzats M, Lafontan M: Desensitization of beta-1 and beta-2, but not beta-3, adrenoceptor-mediated lipolytic responses of adipocytes after long-term norepinephrine infusion. J Pharmacol Exp Ther. 1993 Apr;265(1):237-47.@@Galitzky J, Carpene C, Lafontan M, Berlan M: [Specific stimulation of adipose tissue adrenergic beta 3 receptors by octopamine]. C R Acad Sci III. 1993;316(5):519-23.@@Tamaoki J, Chiyotani A, Sakai N, Konno K: Stimulation of ciliary motility mediated by atypical beta-adrenoceptor in canine bronchial epithelium. Life Sci. 1993;53(20):1509-15.@@Mersmann HJ: Overview of the effects of beta-adrenergic receptor agonists on animal growth including mechanisms of action. J Anim Sci. 1998 Jan;76(1):160-72. |
| Groups | Approved |
| Direct Classification | Catechols |
| SMILES | NC[C@H](O)C1=CC(O)=C(O)C=C1 |
| Pathways | Remifentanil Action Pathway; Hydrocodone Action Pathway; Sufentanil Action Pathway; Fluoxetine Action Pathway; Morphine Action Pathway; 3-Methylthiofentanyl Action Pathway; Benzocaine Action Pathway; Oxybuprocaine Action Pathway; Codeine Action Pathway; Alkaptonuria; Tyrosine Hydroxylase Deficiency; Ketobemidone Action Pathway; Propoxyphene Action Pathway; Dihydromorphine Action Pathway; Nicotine Action Pathway; Proparacaine Action Pathway; Methadyl Acetate Action Pathway; Hawkinsinuria; Oxymorphone Action Pathway; Dimethylthiambutene Action Pathway; Fentanyl Action Pathway; Dopamine beta-Hydroxylase Deficiency; Lidocaine (Local Anaesthetic) Action Pathway; Monoamine Oxidase-A Deficiency (MAO-A); Aromatic L-Aminoacid Decarboxylase Deficiency; Hydromorphone Action Pathway; Tyrosinemia, Transient, of the Newborn; Anileridine Action Pathway; Bupivacaine Action Pathway; Levallorphan Action Pathway |
| PharmGKB | PA450649 |
| ChEMBL | CHEMBL1437 |
