| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS30086012 | HIV | ENSG00000188778.6 | protein_coding | ADRB3 | No | No | 155 | A8KAG8 P13945 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | ADRB3 |
|---|---|
| DrugBank ID | DB06262 |
| Drug Name | Droxidopa |
| Target ID | BE0001012 |
| UniProt ID | P13945 |
| Regulation Type | agonist |
| PubMed IDs | 19434307; 9464897; 19110970; 18064417 |
| Citations | Coman OA, Paunescu H, Ghita I, Coman L, Badararu A, Fulga I: Beta 3 adrenergic receptors: molecular, histological, functional and pharmacological approaches. Rom J Morphol Embryol. 2009;50(2):169-79.@@Mersmann HJ: Overview of the effects of beta-adrenergic receptor agonists on animal growth including mechanisms of action. J Anim Sci. 1998 Jan;76(1):160-72.@@El-Armouche A, Eschenhagen T: Beta-adrenergic stimulation and myocardial function in the failing heart. Heart Fail Rev. 2009 Dec;14(4):225-41. doi: 10.1007/s10741-008-9132-8.@@Gilsbach R, Hein L: Presynaptic metabotropic receptors for acetylcholine and adrenaline/noradrenaline. Handb Exp Pharmacol. 2008;(184):261-88. |
| Groups | Approved; Investigational |
| Direct Classification | Tyrosine and derivatives |
| SMILES | N[C@@H]([C@H](O)C1=CC(O)=C(O)C=C1)C(O)=O |
| Pathways | |
| PharmGKB | PA164748386 |
| ChEMBL | CHEMBL2103827 |
