Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS10010882HBVENSG00000105976.16protein_codingMETYesNo4233E6Y365
P08581
TVIS30067833HIVENSG00000105976.16protein_codingMETYesNo4233E6Y365
P08581
TVIS20012857HPVENSG00000105976.16protein_codingMETYesNo4233E6Y365
P08581
TVIS20062294HPVENSG00000105976.16protein_codingMETYesNo4233E6Y365
P08581
TVIS20023366HPVENSG00000105976.16protein_codingMETYesNo4233E6Y365
P08581
TVIS20022730HPVENSG00000105976.16protein_codingMETYesNo4233E6Y365
P08581
TVIS20061784HPVENSG00000105976.16protein_codingMETYesNo4233E6Y365
P08581
TVIS44016703HTLV-1ENSG00000105976.16protein_codingMETYesNo4233E6Y365
P08581
TVIS44049057HTLV-1ENSG00000105976.16protein_codingMETYesNo4233E6Y365
P08581
TCGA Plot Options
Drug Information
GeneMET
DrugBank IDDB02152
Drug NameK-252a
Target IDBE0000915
UniProt IDP08581
Regulation Type
PubMed IDs17139284; 17016423; 10592235
CitationsOverington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.@@Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34.@@Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42.
GroupsExperimental
Direct ClassificationIndolocarbazoles
SMILES[H][C@]12C[C@](O)(C(=O)OC)[C@](C)(O1)N1C3=C(C=CC=C3)C3=C4CNC(=O)C4=C4C5=CC=CC=C5N2C4=C13
Pathways
PharmGKB
ChEMBLCHEMBL281948