Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS10010853HBVENSG00000170214.5protein_codingADRA1BNoNo147P35368
TVIS10010854HBVENSG00000170214.5protein_codingADRA1BNoNo147P35368
TVIS20024833HPVENSG00000170214.5protein_codingADRA1BNoNo147P35368
TVIS20065388HPVENSG00000170214.5protein_codingADRA1BNoNo147P35368
TVIS20023848HPVENSG00000170214.5protein_codingADRA1BNoNo147P35368
TVIS44016411HTLV-1ENSG00000170214.5protein_codingADRA1BNoNo147P35368
TVIS44025476HTLV-1ENSG00000170214.5protein_codingADRA1BNoNo147P35368
TVIS44000687HTLV-1ENSG00000170214.5protein_codingADRA1BNoNo147P35368
TVIS44029351HTLV-1ENSG00000170214.5protein_codingADRA1BNoNo147P35368
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Drug Information
GeneADRA1B
DrugBank IDDB00668
Drug NameEpinephrine
Target IDBE0000575
UniProt IDP35368
Regulation Typeagonist
PubMed IDs20954794; 19730427; 20412040; 20857090
CitationsCotecchia S: The alpha1-adrenergic receptors: diversity of signaling networks and regulation. J Recept Signal Transduct Res. 2010 Dec;30(6):410-9. doi: 10.3109/10799893.2010.518152. Epub 2010 Oct 18.@@Shieh JP, Chu CC, Wang JJ, Lin MT: Epinephrine, phenylephrine, and methoxamine induce infiltrative anesthesia via alpha1-adrenoceptors in rats. Acta Pharmacol Sin. 2009 Sep;30(9):1227-36. doi: 10.1038/aps.2009.129.@@Du L, Li M: Modeling the interactions between alpha(1)-adrenergic receptors and their antagonists. Curr Comput Aided Drug Des. 2010 Sep;6(3):165-78.@@Jensen BC, Swigart PM, Montgomery MD, Simpson PC: Functional alpha-1B adrenergic receptors on human epicardial coronary artery endothelial cells. Naunyn Schmiedebergs Arch Pharmacol. 2010 Dec;382(5-6):475-82. doi: 10.1007/s00210-010-0558-x. Epub 2010 Sep 22.
GroupsApproved; Vet_approved
Direct ClassificationCatechols
SMILESCNC[C@H](O)C1=CC(O)=C(O)C=C1
PathwaysTyrosine Metabolism; Disulfiram Action Pathway; Aromatic L-Aminoacid Decarboxylase Deficiency; Monoamine Oxidase-A Deficiency (MAO-A); Catecholamine Biosynthesis; Tyrosinemia, Transient, of the Newborn; Hawkinsinuria; Dopamine beta-Hydroxylase Deficiency; Tyrosinemia Type I; Epinephrine Action Pathway; Alkaptonuria; Tyrosine Hydroxylase Deficiency
PharmGKBPA449470
ChEMBLCHEMBL679