Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS10010853HBVENSG00000170214.5protein_codingADRA1BNoNo147P35368
TVIS10010854HBVENSG00000170214.5protein_codingADRA1BNoNo147P35368
TVIS20024833HPVENSG00000170214.5protein_codingADRA1BNoNo147P35368
TVIS20065388HPVENSG00000170214.5protein_codingADRA1BNoNo147P35368
TVIS20023848HPVENSG00000170214.5protein_codingADRA1BNoNo147P35368
TVIS44016411HTLV-1ENSG00000170214.5protein_codingADRA1BNoNo147P35368
TVIS44025476HTLV-1ENSG00000170214.5protein_codingADRA1BNoNo147P35368
TVIS44000687HTLV-1ENSG00000170214.5protein_codingADRA1BNoNo147P35368
TVIS44029351HTLV-1ENSG00000170214.5protein_codingADRA1BNoNo147P35368
TCGA Plot Options
Drug Information
GeneADRA1B
DrugBank IDDB01579
Drug NamePhendimetrazine
Target IDBE0000575
UniProt IDP35368
Regulation Typeagonist
PubMed IDs17139284; 17016423; 16265126; 11054601; 11752352; 17017961
CitationsOverington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.@@Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34.@@Bray GA: Drug Insight: appetite suppressants. Nat Clin Pract Gastroenterol Hepatol. 2005 Feb;2(2):89-95.@@Bray GA: A concise review on the therapeutics of obesity. Nutrition. 2000 Oct;16(10):953-60.@@Chen X, Ji ZL, Chen YZ: TTD: Therapeutic Target Database. Nucleic Acids Res. 2002 Jan 1;30(1):412-5.@@Rothman RB, Baumann MH: Therapeutic potential of monoamine transporter substrates. Curr Top Med Chem. 2006;6(17):1845-59.
GroupsApproved; Illicit
Direct ClassificationPhenylmorpholines
SMILESC[C@H]1[C@@H](OCCN1C)C1=CC=CC=C1
Pathways
PharmGKBPA450902
ChEMBLCHEMBL1615439