| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10010853 | HBV | ENSG00000170214.5 | protein_coding | ADRA1B | No | No | 147 | P35368 |
| TVIS10010854 | HBV | ENSG00000170214.5 | protein_coding | ADRA1B | No | No | 147 | P35368 |
| TVIS20024833 | HPV | ENSG00000170214.5 | protein_coding | ADRA1B | No | No | 147 | P35368 |
| TVIS20065388 | HPV | ENSG00000170214.5 | protein_coding | ADRA1B | No | No | 147 | P35368 |
| TVIS20023848 | HPV | ENSG00000170214.5 | protein_coding | ADRA1B | No | No | 147 | P35368 |
| TVIS44016411 | HTLV-1 | ENSG00000170214.5 | protein_coding | ADRA1B | No | No | 147 | P35368 |
| TVIS44025476 | HTLV-1 | ENSG00000170214.5 | protein_coding | ADRA1B | No | No | 147 | P35368 |
| TVIS44000687 | HTLV-1 | ENSG00000170214.5 | protein_coding | ADRA1B | No | No | 147 | P35368 |
| TVIS44029351 | HTLV-1 | ENSG00000170214.5 | protein_coding | ADRA1B | No | No | 147 | P35368 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | ADRA1B |
|---|---|
| DrugBank ID | DB01142 |
| Drug Name | Doxepin |
| Target ID | BE0000575 |
| UniProt ID | P35368 |
| Regulation Type | antagonist |
| PubMed IDs | 7855217; 19179941; 6086881 |
| Citations | Cusack B, Nelson A, Richelson E: Binding of antidepressants to human brain receptors: focus on newer generation compounds. Psychopharmacology (Berl). 1994 May;114(4):559-65.@@Stahl SM: Selective histamine H1 antagonism: novel hypnotic and pharmacologic actions challenge classical notions of antihistamines. CNS Spectr. 2008 Dec;13(12):1027-38.@@Richelson E, Nelson A: Antagonism by antidepressants of neurotransmitter receptors of normal human brain in vitro. J Pharmacol Exp Ther. 1984 Jul;230(1):94-102. |
| Groups | Approved; Investigational |
| Direct Classification | Dibenzoxepines |
| SMILES | [H]C(CCN(C)C)=C1C2=CC=CC=C2COC2=CC=CC=C12 |
| Pathways | Doxepin Metabolism Pathway; Doxepin H1-Antihistamine Action |
| PharmGKB | PA449409 |
| ChEMBL | CHEMBL1628227 |
