Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS10010853HBVENSG00000170214.5protein_codingADRA1BNoNo147P35368
TVIS10010854HBVENSG00000170214.5protein_codingADRA1BNoNo147P35368
TVIS20024833HPVENSG00000170214.5protein_codingADRA1BNoNo147P35368
TVIS20065388HPVENSG00000170214.5protein_codingADRA1BNoNo147P35368
TVIS20023848HPVENSG00000170214.5protein_codingADRA1BNoNo147P35368
TVIS44016411HTLV-1ENSG00000170214.5protein_codingADRA1BNoNo147P35368
TVIS44025476HTLV-1ENSG00000170214.5protein_codingADRA1BNoNo147P35368
TVIS44000687HTLV-1ENSG00000170214.5protein_codingADRA1BNoNo147P35368
TVIS44029351HTLV-1ENSG00000170214.5protein_codingADRA1BNoNo147P35368
TCGA Plot Options
Drug Information
GeneADRA1B
DrugBank IDDB00321
Drug NameAmitriptyline
Target IDBE0000575
UniProt IDP35368
Regulation Typeantagonist
PubMed IDs20363235
CitationsNojimoto FD, Mueller A, Hebeler-Barbosa F, Akinaga J, Lima V, Kiguti LR, Pupo AS: The tricyclic antidepressants amitriptyline, nortriptyline and imipramine are weak antagonists of human and rat alpha1B-adrenoceptors. Neuropharmacology. 2010 Jul-Aug;59(1-2):49-57. doi: 10.1016/j.neuropharm.2010.03.015. Epub 2010 Apr 2.
GroupsApproved
Direct ClassificationDibenzocycloheptenes
SMILESCN(C)CCC=C1C2=CC=CC=C2CCC2=CC=CC=C12
Pathways
PharmGKBPA448385
ChEMBLCHEMBL629