Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS10010853HBVENSG00000170214.5protein_codingADRA1BNoNo147P35368
TVIS10010854HBVENSG00000170214.5protein_codingADRA1BNoNo147P35368
TVIS20024833HPVENSG00000170214.5protein_codingADRA1BNoNo147P35368
TVIS20065388HPVENSG00000170214.5protein_codingADRA1BNoNo147P35368
TVIS20023848HPVENSG00000170214.5protein_codingADRA1BNoNo147P35368
TVIS44016411HTLV-1ENSG00000170214.5protein_codingADRA1BNoNo147P35368
TVIS44025476HTLV-1ENSG00000170214.5protein_codingADRA1BNoNo147P35368
TVIS44000687HTLV-1ENSG00000170214.5protein_codingADRA1BNoNo147P35368
TVIS44029351HTLV-1ENSG00000170214.5protein_codingADRA1BNoNo147P35368
TCGA Plot Options
Drug Information
GeneADRA1B
DrugBank IDDB06207
Drug NameSilodosin
Target IDBE0000575
UniProt IDP35368
Regulation Typeantagonist
PubMed IDs21114397; 12002804; 24198606
CitationsLepor H, Hill LA: Silodosin for the treatment of benign prostatic hyperplasia: pharmacology and cardiovascular tolerability. Pharmacotherapy. 2010 Dec;30(12):1303-12. doi: 10.1592/phco.30.12.1303.@@Sugawara T, Hirasawa A, Hashimoto K, Tsujimoto G: Differences in the subcellular localization of alpha1-adrenoceptor subtypes can affect the subtype selectivity of drugs in a study with the fluorescent ligand BODIPY FL-prazosin. Life Sci. 2002 Mar 22;70(18):2113-24. doi: 10.1016/s0024-3205(01)01533-8.@@Yamanishi T, Mizuno T, Kamai T, Yoshida K, Sakakibara R, Uchiyama T: Management of benign prostatic hyperplasia with silodosin. Open Access J Urol. 2009 Aug 20;1:1-7. doi: 10.2147/rru.s5004.
GroupsApproved
Direct ClassificationIndolecarboxamides and derivatives
SMILESC[C@H](CC1=CC2=C(N(CCCO)CC2)C(=C1)C(N)=O)NCCOC1=CC=CC=C1OCC(F)(F)F
Pathways
PharmGKBPA165291889
ChEMBLCHEMBL24778