| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10046512 | HBV | ENSG00000184984.10 | protein_coding | CHRM5 | No | No | 1133 | P08912 Q8IVW0 |
| TVIS30086165 | HIV | ENSG00000184984.10 | protein_coding | CHRM5 | No | No | 1133 | P08912 Q8IVW0 |
| TVIS30037769 | HIV | ENSG00000184984.10 | protein_coding | CHRM5 | No | No | 1133 | P08912 Q8IVW0 |
| TVIS20007173 | HPV | ENSG00000184984.10 | protein_coding | CHRM5 | No | No | 1133 | P08912 Q8IVW0 |
| TVIS20007241 | HPV | ENSG00000184984.10 | protein_coding | CHRM5 | No | No | 1133 | P08912 Q8IVW0 |
| TVIS20045839 | HPV | ENSG00000184984.10 | protein_coding | CHRM5 | No | No | 1133 | P08912 Q8IVW0 |
| TVIS44041826 | HTLV-1 | ENSG00000184984.10 | protein_coding | CHRM5 | No | No | 1133 | P08912 Q8IVW0 |
Target Gene Table
▼
TCGA Plot Options
▼
Drug Information
▼
| Gene | CHRM5 |
|---|---|
| DrugBank ID | DB01409 |
| Drug Name | Tiotropium |
| Target ID | BE0000247 |
| UniProt ID | P08912 |
| Regulation Type | |
| PubMed IDs | 21870878 |
| Citations | Glossop PA, Watson CA, Price DA, Bunnage ME, Middleton DS, Wood A, James K, Roberts D, Strang RS, Yeadon M, Perros-Huguet C, Clarke NP, Trevethick MA, Machin I, Stuart EF, Evans SM, Harrison AC, Fairman DA, Agoram B, Burrows JL, Feeder N, Fulton CK, Dillon BR, Entwistle DA, Spence FJ: Inhalation by design: novel tertiary amine muscarinic M(3) receptor antagonists with slow off-rate binding kinetics for inhaled once-daily treatment of chronic obstructive pulmonary disease. J Med Chem. 2011 Oct 13;54(19):6888-904. doi: 10.1021/jm200884j. Epub 2011 Sep 20. |
| Groups | Approved |
| Direct Classification | Morpholines |
| SMILES | [H][C@]12O[C@@]1([H])[C@]1([H])C[C@@]([H])(C[C@@]2([H])[N+]1(C)C)OC(=O)C(O)(C1=CC=CS1)C1=CC=CS1 |
| Pathways | |
| PharmGKB | PA164769056 |
| ChEMBL | CHEMBL1900528 |
