| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10046512 | HBV | ENSG00000184984.10 | protein_coding | CHRM5 | No | No | 1133 | P08912 Q8IVW0 |
| TVIS30086165 | HIV | ENSG00000184984.10 | protein_coding | CHRM5 | No | No | 1133 | P08912 Q8IVW0 |
| TVIS30037769 | HIV | ENSG00000184984.10 | protein_coding | CHRM5 | No | No | 1133 | P08912 Q8IVW0 |
| TVIS20007173 | HPV | ENSG00000184984.10 | protein_coding | CHRM5 | No | No | 1133 | P08912 Q8IVW0 |
| TVIS20007241 | HPV | ENSG00000184984.10 | protein_coding | CHRM5 | No | No | 1133 | P08912 Q8IVW0 |
| TVIS20045839 | HPV | ENSG00000184984.10 | protein_coding | CHRM5 | No | No | 1133 | P08912 Q8IVW0 |
| TVIS44041826 | HTLV-1 | ENSG00000184984.10 | protein_coding | CHRM5 | No | No | 1133 | P08912 Q8IVW0 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | CHRM5 |
|---|---|
| DrugBank ID | DB09076 |
| Drug Name | Umeclidinium |
| Target ID | BE0000247 |
| UniProt ID | P08912 |
| Regulation Type | antagonist |
| PubMed IDs | 23435542 |
| Citations | Salmon M, Luttmann MA, Foley JJ, Buckley PT, Schmidt DB, Burman M, Webb EF, DeHaas CJ, Kotzer CJ, Barrett VJ, Slack RJ, Sarau HM, Palovich MR, Laine DI, Hay DW, Rumsey WL: Pharmacological characterization of GSK573719 (umeclidinium): a novel, long-acting, inhaled antagonist of the muscarinic cholinergic receptors for treatment of pulmonary diseases. J Pharmacol Exp Ther. 2013 May;345(2):260-70. doi: 10.1124/jpet.112.202051. Epub 2013 Feb 22. |
| Groups | Approved |
| Direct Classification | Diphenylmethanes |
| SMILES | OC(C1=CC=CC=C1)(C1=CC=CC=C1)C12CC[N+](CCOCC3=CC=CC=C3)(CC1)CC2 |
| Pathways | |
| PharmGKB | |
| ChEMBL | CHEMBL1187833 |
