Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS10046512HBVENSG00000184984.10protein_codingCHRM5NoNo1133P08912
Q8IVW0
TVIS30086165HIVENSG00000184984.10protein_codingCHRM5NoNo1133P08912
Q8IVW0
TVIS30037769HIVENSG00000184984.10protein_codingCHRM5NoNo1133P08912
Q8IVW0
TVIS20007173HPVENSG00000184984.10protein_codingCHRM5NoNo1133P08912
Q8IVW0
TVIS20007241HPVENSG00000184984.10protein_codingCHRM5NoNo1133P08912
Q8IVW0
TVIS20045839HPVENSG00000184984.10protein_codingCHRM5NoNo1133P08912
Q8IVW0
TVIS44041826HTLV-1ENSG00000184984.10protein_codingCHRM5NoNo1133P08912
Q8IVW0
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Drug Information
GeneCHRM5
DrugBank IDDB01591
Drug NameSolifenacin
Target IDBE0000247
UniProt IDP08912
Regulation Typeantagonist
PubMed IDs19029429
CitationsMansfield KJ, Chandran JJ, Vaux KJ, Millard RJ, Christopoulos A, Mitchelson FJ, Burcher E: Comparison of receptor binding characteristics of commonly used muscarinic antagonists in human bladder detrusor and mucosa. J Pharmacol Exp Ther. 2009 Mar;328(3):893-9. doi: 10.1124/jpet.108.145508. Epub 2008 Nov 24.
GroupsApproved
Direct Classification1-phenyltetrahydroisoquinolines
SMILESO=C(O[C@H]1CN2CCC1CC2)N1CCC2=CC=CC=C2[C@@H]1C1=CC=CC=C1
Pathways
PharmGKBPA164783810
ChEMBLCHEMBL1734