Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS10004907HBVENSG00000070915.10protein_codingSLC12A3NoNo6559J3QSS1
P55017
TVIS10002672HBVENSG00000070915.10protein_codingSLC12A3NoNo6559J3QSS1
P55017
TVIS10022547HBVENSG00000070915.10protein_codingSLC12A3NoNo6559J3QSS1
P55017
TVIS10027635HBVENSG00000070915.10protein_codingSLC12A3NoNo6559J3QSS1
P55017
TVIS10049843HBVENSG00000070915.10protein_codingSLC12A3NoNo6559J3QSS1
P55017
TVIS30041140HIVENSG00000070915.10protein_codingSLC12A3NoNo6559J3QSS1
P55017
TVIS20052662HPVENSG00000070915.10protein_codingSLC12A3NoNo6559J3QSS1
P55017
TVIS44023796HTLV-1ENSG00000070915.10protein_codingSLC12A3NoNo6559J3QSS1
P55017
TVIS44023797HTLV-1ENSG00000070915.10protein_codingSLC12A3NoNo6559J3QSS1
P55017
TVIS44047476HTLV-1ENSG00000070915.10protein_codingSLC12A3NoNo6559J3QSS1
P55017
TCGA Plot Options
Drug Information
GeneSLC12A3
DrugBank IDDB00562
Drug NameBenzthiazide
Target IDBE0000419
UniProt IDP55017
Regulation Typeinhibitor
PubMed IDs31285285; 12538756
CitationsBlanchard A, Vallet M, Dubourg L, Hureaux M, Allard J, Haymann JP, de la Faille R, Arnoux A, Dinut A, Bergerot D, Becker PH, Courand PY, Baron S, Houillier P, Tack I, Devuyst O, Jeunemaitre X, Azizi M, Vargas-Poussou R: Resistance to Insulin in Patients with Gitelman Syndrome and a Subtle Intermediate Phenotype in Heterozygous Carriers: A Cross-Sectional Study. J Am Soc Nephrol. 2019 Aug;30(8):1534-1545. doi: 10.1681/ASN.2019010031. Epub 2019 Jul 8.@@Ellison DH: The thiazide-sensitive na-cl cotransporter and human disease: reemergence of an old player. J Am Soc Nephrol. 2003 Feb;14(2):538-40.
GroupsApproved
Direct Classification1,2,4-benzothiadiazine-1,1-dioxides
SMILESNS(=O)(=O)C1=CC2=C(C=C1Cl)N=C(CSCC1=CC=CC=C1)NS2(=O)=O
Pathways
PharmGKBPA164776841
ChEMBLCHEMBL1201039