| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10004907 | HBV | ENSG00000070915.10 | protein_coding | SLC12A3 | No | No | 6559 | J3QSS1 P55017 |
| TVIS10002672 | HBV | ENSG00000070915.10 | protein_coding | SLC12A3 | No | No | 6559 | J3QSS1 P55017 |
| TVIS10022547 | HBV | ENSG00000070915.10 | protein_coding | SLC12A3 | No | No | 6559 | J3QSS1 P55017 |
| TVIS10027635 | HBV | ENSG00000070915.10 | protein_coding | SLC12A3 | No | No | 6559 | J3QSS1 P55017 |
| TVIS10049843 | HBV | ENSG00000070915.10 | protein_coding | SLC12A3 | No | No | 6559 | J3QSS1 P55017 |
| TVIS30041140 | HIV | ENSG00000070915.10 | protein_coding | SLC12A3 | No | No | 6559 | J3QSS1 P55017 |
| TVIS20052662 | HPV | ENSG00000070915.10 | protein_coding | SLC12A3 | No | No | 6559 | J3QSS1 P55017 |
| TVIS44023796 | HTLV-1 | ENSG00000070915.10 | protein_coding | SLC12A3 | No | No | 6559 | J3QSS1 P55017 |
| TVIS44023797 | HTLV-1 | ENSG00000070915.10 | protein_coding | SLC12A3 | No | No | 6559 | J3QSS1 P55017 |
| TVIS44047476 | HTLV-1 | ENSG00000070915.10 | protein_coding | SLC12A3 | No | No | 6559 | J3QSS1 P55017 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | SLC12A3 |
|---|---|
| DrugBank ID | DB00808 |
| Drug Name | Indapamide |
| Target ID | BE0000419 |
| UniProt ID | P55017 |
| Regulation Type | inhibitor |
| PubMed IDs | 23729436; 24444254; 20528637 |
| Citations | Ma F, Lin F, Chen C, Cheng J, Zeldin DC, Wang Y, Wang DW: Indapamide lowers blood pressure by increasing production of epoxyeicosatrienoic acids in the kidney. Mol Pharmacol. 2013 Aug;84(2):286-95. doi: 10.1124/mol.113.085878. Epub 2013 May 31.@@Tamargo J, Segura J, Ruilope LM: Diuretics in the treatment of hypertension. Part 1: thiazide and thiazide-like diuretics. Expert Opin Pharmacother. 2014 Mar;15(4):527-47. doi: 10.1517/14656566.2014.879118. Epub 2014 Jan 20.@@Duarte JD, Cooper-DeHoff RM: Mechanisms for blood pressure lowering and metabolic effects of thiazide and thiazide-like diuretics. Expert Rev Cardiovasc Ther. 2010 Jun;8(6):793-802. doi: 10.1586/erc.10.27. |
| Groups | Approved |
| Direct Classification | Benzenesulfonamides |
| SMILES | CC1CC2=CC=CC=C2N1NC(=O)C1=CC(=C(Cl)C=C1)S(N)(=O)=O |
| Pathways | Indapamide Action Pathway |
| PharmGKB | PA449975 |
| ChEMBL | CHEMBL406 |
