| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10004907 | HBV | ENSG00000070915.10 | protein_coding | SLC12A3 | No | No | 6559 | J3QSS1 P55017 |
| TVIS10002672 | HBV | ENSG00000070915.10 | protein_coding | SLC12A3 | No | No | 6559 | J3QSS1 P55017 |
| TVIS10022547 | HBV | ENSG00000070915.10 | protein_coding | SLC12A3 | No | No | 6559 | J3QSS1 P55017 |
| TVIS10027635 | HBV | ENSG00000070915.10 | protein_coding | SLC12A3 | No | No | 6559 | J3QSS1 P55017 |
| TVIS10049843 | HBV | ENSG00000070915.10 | protein_coding | SLC12A3 | No | No | 6559 | J3QSS1 P55017 |
| TVIS30041140 | HIV | ENSG00000070915.10 | protein_coding | SLC12A3 | No | No | 6559 | J3QSS1 P55017 |
| TVIS20052662 | HPV | ENSG00000070915.10 | protein_coding | SLC12A3 | No | No | 6559 | J3QSS1 P55017 |
| TVIS44023796 | HTLV-1 | ENSG00000070915.10 | protein_coding | SLC12A3 | No | No | 6559 | J3QSS1 P55017 |
| TVIS44023797 | HTLV-1 | ENSG00000070915.10 | protein_coding | SLC12A3 | No | No | 6559 | J3QSS1 P55017 |
| TVIS44047476 | HTLV-1 | ENSG00000070915.10 | protein_coding | SLC12A3 | No | No | 6559 | J3QSS1 P55017 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | SLC12A3 |
|---|---|
| DrugBank ID | DB01021 |
| Drug Name | Trichlormethiazide |
| Target ID | BE0000419 |
| UniProt ID | P55017 |
| Regulation Type | inhibitor |
| PubMed IDs | 17414671; 14610216; 20187262; 11752352 |
| Citations | Li J, Wang DH: Function and regulation of epithelial sodium transporters in the kidney of a salt-sensitive hypertensive rat model. J Hypertens. 2007 May;25(5):1065-72.@@Hasannejad H, Takeda M, Taki K, Shin HJ, Babu E, Jutabha P, Khamdang S, Aleboyeh M, Onozato ML, Tojo A, Enomoto A, Anzai N, Narikawa S, Huang XL, Niwa T, Endou H: Interactions of human organic anion transporters with diuretics. J Pharmacol Exp Ther. 2004 Mar;308(3):1021-9. Epub 2003 Nov 10.@@Smith SM: Thiazide diuretics. N Engl J Med. 2010 Feb 18;362(7):659-60; author reply 660.@@Chen X, Ji ZL, Chen YZ: TTD: Therapeutic Target Database. Nucleic Acids Res. 2002 Jan 1;30(1):412-5. |
| Groups | Approved; Vet_approved |
| Direct Classification | 1,2,4-benzothiadiazine-1,1-dioxides |
| SMILES | NS(=O)(=O)C1=C(Cl)C=C2NC(NS(=O)(=O)C2=C1)C(Cl)Cl |
| Pathways | Trichlormethiazide Action Pathway |
| PharmGKB | PA164752426 |
| ChEMBL | CHEMBL1054 |
