| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10004907 | HBV | ENSG00000070915.10 | protein_coding | SLC12A3 | No | No | 6559 | J3QSS1 P55017 |
| TVIS10002672 | HBV | ENSG00000070915.10 | protein_coding | SLC12A3 | No | No | 6559 | J3QSS1 P55017 |
| TVIS10022547 | HBV | ENSG00000070915.10 | protein_coding | SLC12A3 | No | No | 6559 | J3QSS1 P55017 |
| TVIS10027635 | HBV | ENSG00000070915.10 | protein_coding | SLC12A3 | No | No | 6559 | J3QSS1 P55017 |
| TVIS10049843 | HBV | ENSG00000070915.10 | protein_coding | SLC12A3 | No | No | 6559 | J3QSS1 P55017 |
| TVIS30041140 | HIV | ENSG00000070915.10 | protein_coding | SLC12A3 | No | No | 6559 | J3QSS1 P55017 |
| TVIS20052662 | HPV | ENSG00000070915.10 | protein_coding | SLC12A3 | No | No | 6559 | J3QSS1 P55017 |
| TVIS44023796 | HTLV-1 | ENSG00000070915.10 | protein_coding | SLC12A3 | No | No | 6559 | J3QSS1 P55017 |
| TVIS44023797 | HTLV-1 | ENSG00000070915.10 | protein_coding | SLC12A3 | No | No | 6559 | J3QSS1 P55017 |
| TVIS44047476 | HTLV-1 | ENSG00000070915.10 | protein_coding | SLC12A3 | No | No | 6559 | J3QSS1 P55017 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | SLC12A3 |
|---|---|
| DrugBank ID | DB01325 |
| Drug Name | Quinethazone |
| Target ID | BE0000419 |
| UniProt ID | P55017 |
| Regulation Type | inhibitor |
| PubMed IDs | 20528637; 19474192; 12538756; 19636250 |
| Citations | Duarte JD, Cooper-DeHoff RM: Mechanisms for blood pressure lowering and metabolic effects of thiazide and thiazide-like diuretics. Expert Rev Cardiovasc Ther. 2010 Jun;8(6):793-802. doi: 10.1586/erc.10.27.@@Gamba G: The thiazide-sensitive Na+-Cl- cotransporter: molecular biology, functional properties, and regulation by WNKs. Am J Physiol Renal Physiol. 2009 Oct;297(4):F838-48. doi: 10.1152/ajprenal.00159.2009. Epub 2009 May 27.@@Ellison DH: The thiazide-sensitive na-cl cotransporter and human disease: reemergence of an old player. J Am Soc Nephrol. 2003 Feb;14(2):538-40.@@Ko B, Hoover RS: Molecular physiology of the thiazide-sensitive sodium-chloride cotransporter. Curr Opin Nephrol Hypertens. 2009 Sep;18(5):421-7. doi: 10.1097/MNH.0b013e32832f2fcb. |
| Groups | Approved |
| Direct Classification | Quinazolines |
| SMILES | CCC1NC(=O)C2=CC(=C(Cl)C=C2N1)S(N)(=O)=O |
| Pathways | Quinethazone Action Pathway |
| PharmGKB | PA164760863 |
| ChEMBL | CHEMBL1532 |
