Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS10018193HBVENSG00000082556.14protein_codingOPRK1NoNo4986P41145
TVIS20013017HPVENSG00000082556.14protein_codingOPRK1NoNo4986P41145
TVIS20021008HPVENSG00000082556.14protein_codingOPRK1NoNo4986P41145
TVIS20013016HPVENSG00000082556.14protein_codingOPRK1NoNo4986P41145
TVIS20062745HPVENSG00000082556.14protein_codingOPRK1NoNo4986P41145
TVIS44020000HTLV-1ENSG00000082556.14protein_codingOPRK1NoNo4986P41145
TCGA Plot Options
Drug Information
GeneOPRK1
DrugBank IDDB01497
Drug NameEtorphine
Target IDBE0000632
UniProt IDP41145
Regulation Typeagonist
PubMed IDs7739347; 17720886; 16433932
CitationsNiwa M, al-Essa LY, Ohta S, Kohno K, Nozaki M, Tsurumi K, Iwamura T, Kataoka T: Opioid receptor interaction and adenylyl cyclase inhibition of dihydroetorphine: direct comparison with etorphine. Life Sci. 1995;56(21):PL395-400.@@Wannemacher KM, Yadav PN, Howells RD: A select set of opioid ligands induce up-regulation by promoting the maturation and stability of the rat kappa-opioid receptor in human embryonic kidney 293 cells. J Pharmacol Exp Ther. 2007 Nov;323(2):614-25. Epub 2007 Aug 24.@@Gharagozlou P, Hashemi E, DeLorey TM, Clark JD, Lameh J: Pharmacological profiles of opioid ligands at kappa opioid receptors. BMC Pharmacol. 2006 Jan 25;6:3.
GroupsIllicit; Vet_approved
Direct ClassificationMorphinans
SMILES[H][C@]12CC3=C4C(OC5[C@@]4(CCN1C)[C@]21CC(C(C)(O)CCC)C5(OC)C=C1)=C(O)C=C3
Pathways
PharmGKB
ChEMBL