| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10018193 | HBV | ENSG00000082556.14 | protein_coding | OPRK1 | No | No | 4986 | P41145 |
| TVIS20013017 | HPV | ENSG00000082556.14 | protein_coding | OPRK1 | No | No | 4986 | P41145 |
| TVIS20021008 | HPV | ENSG00000082556.14 | protein_coding | OPRK1 | No | No | 4986 | P41145 |
| TVIS20013016 | HPV | ENSG00000082556.14 | protein_coding | OPRK1 | No | No | 4986 | P41145 |
| TVIS20062745 | HPV | ENSG00000082556.14 | protein_coding | OPRK1 | No | No | 4986 | P41145 |
| TVIS44020000 | HTLV-1 | ENSG00000082556.14 | protein_coding | OPRK1 | No | No | 4986 | P41145 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | OPRK1 |
|---|---|
| DrugBank ID | DB00370 |
| Drug Name | Mirtazapine |
| Target ID | BE0000632 |
| UniProt ID | P41145 |
| Regulation Type | agonist |
| PubMed IDs | 12372565; 22708686; 30155392 |
| Citations | Schreiber S, Rigai T, Katz Y, Pick CG: The antinociceptive effect of mirtazapine in mice is mediated through serotonergic, noradrenergic and opioid mechanisms. Brain Res Bull. 2002 Sep 30;58(6):601-5.@@Olianas MC, Dedoni S, Onali P: The atypical antidepressant mianserin exhibits agonist activity at kappa-opioid receptors. Br J Pharmacol. 2012 Nov;167(6):1329-41. doi: 10.1111/j.1476-5381.2012.02078.x.@@Peckham AM, De La Cruz A, Dufresne RL: Kappa opioid receptor antagonism: Are opioids the answer for treatment resistant depression? Ment Health Clin. 2018 Jun 29;8(4):175-183. doi: 10.9740/mhc.2018.07.175. eCollection 2018 Jul. |
| Groups | Approved |
| Direct Classification | Piperazinoazepines |
| SMILES | CN1CCN2C(C1)C1=CC=CC=C1CC1=C2N=CC=C1 |
| Pathways | Mirtazapine H1-Antihistamine Action |
| PharmGKB | PA450522 |
| ChEMBL | CHEMBL654 |
