| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10018193 | HBV | ENSG00000082556.14 | protein_coding | OPRK1 | No | No | 4986 | P41145 |
| TVIS20013017 | HPV | ENSG00000082556.14 | protein_coding | OPRK1 | No | No | 4986 | P41145 |
| TVIS20021008 | HPV | ENSG00000082556.14 | protein_coding | OPRK1 | No | No | 4986 | P41145 |
| TVIS20013016 | HPV | ENSG00000082556.14 | protein_coding | OPRK1 | No | No | 4986 | P41145 |
| TVIS20062745 | HPV | ENSG00000082556.14 | protein_coding | OPRK1 | No | No | 4986 | P41145 |
| TVIS44020000 | HTLV-1 | ENSG00000082556.14 | protein_coding | OPRK1 | No | No | 4986 | P41145 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | OPRK1 |
|---|---|
| DrugBank ID | DB00321 |
| Drug Name | Amitriptyline |
| Target ID | BE0000632 |
| UniProt ID | P41145 |
| Regulation Type | agonist |
| PubMed IDs | 19828880; 3013380 |
| Citations | Onali P, Dedoni S, Olianas MC: Direct agonist activity of tricyclic antidepressants at distinct opioid receptor subtypes. J Pharmacol Exp Ther. 2010 Jan;332(1):255-65. doi: 10.1124/jpet.109.159939. Epub 2009 Oct 14.@@Carydakis C, Bourhim N, Giraud P, Cantau P, Oliver C, Castanas E: [Direct interaction of tricyclic antidepressants with opiate binding sites in the bovine adrenal medulla]. C R Acad Sci III. 1986;302(11):419-22. |
| Groups | Approved |
| Direct Classification | Dibenzocycloheptenes |
| SMILES | CN(C)CCC=C1C2=CC=CC=C2CCC2=CC=CC=C12 |
| Pathways | |
| PharmGKB | PA448385 |
| ChEMBL | CHEMBL629 |
