Target Gene Table ▼
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS10004169HBVENSG00000133019.12protein_codingCHRM3NoNo1131P20309
TVIS10006529HBVENSG00000133019.12protein_codingCHRM3NoNo1131P20309
TVIS10013404HBVENSG00000133019.12protein_codingCHRM3NoNo1131P20309
TVIS10013405HBVENSG00000133019.12protein_codingCHRM3NoNo1131P20309
TVIS10013406HBVENSG00000133019.12protein_codingCHRM3NoNo1131P20309
TVIS10013407HBVENSG00000133019.12protein_codingCHRM3NoNo1131P20309
TVIS10013408HBVENSG00000133019.12protein_codingCHRM3NoNo1131P20309
TVIS10013409HBVENSG00000133019.12protein_codingCHRM3NoNo1131P20309
TVIS10013410HBVENSG00000133019.12protein_codingCHRM3NoNo1131P20309
TVIS10013411HBVENSG00000133019.12protein_codingCHRM3NoNo1131P20309
TCGA Plot Options ▼
Drug Information ▼
GeneCHRM3
DrugBank IDDB01085
Drug NamePilocarpine
Target IDBE0000045
UniProt IDP20309
Regulation Typeagonist
PubMed IDs10372814; 32310588; 28893976
CitationsWang H, Shi H, Lu Y, Yang B, Wang Z: Pilocarpine modulates the cellular electrical properties of mammalian hearts by activating a cardiac M3 receptor and a K+ current. Br J Pharmacol. 1999 Apr;126(8):1725-34. doi: 10.1038/sj.bjp.0702486.@@Panarese V, Moshirfar M: Pilocarpine. .@@Pronin AN, Wang Q, Slepak VZ: Teaching an Old Drug New Tricks: Agonism, Antagonism, and Biased Signaling of Pilocarpine through M3 Muscarinic Acetylcholine Receptor. Mol Pharmacol. 2017 Nov;92(5):601-612. doi: 10.1124/mol.117.109678. Epub 2017 Sep 11.
GroupsApproved; Investigational
Direct ClassificationAlkaloids and derivatives
SMILESCC[C@H]1[C@@H](CC2=CN=CN2C)COC1=O
Pathways
PharmGKBPA450962
ChEMBLCHEMBL550