| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS44035147 | HTLV-1 | ENSG00000189221.11 | protein_coding | MAOA | No | No | 4128 | P21397 Q49A63 Q53YE7 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | MAOA |
|---|---|
| DrugBank ID | DB00191 |
| Drug Name | Phentermine |
| Target ID | BE0002198 |
| UniProt ID | P21397 |
| Regulation Type | antagonist |
| PubMed IDs | 10231134; 10799660; 11673765; 11911838 |
| Citations | Rothman RB: Is phentermine an inhibitor of monoamine oxidase? A critical appraisal. Synapse. 1999 May;32(2):141-5.@@Ulus IH, Maher TJ, Wurtman RJ: Characterization of phentermine and related compounds as monoamine oxidase (MAO) inhibitors. Biochem Pharmacol. 2000 Jun 15;59(12):1611-21.@@Kilpatrick IC, Traut M, Heal DJ: Monoamine oxidase inhibition is unlikely to be relevant to the risks associated with phentermine and fenfluramine: a comparison with their abilities to evoke monoamine release. Int J Obes Relat Metab Disord. 2001 Oct;25(10):1454-8.@@Nandigama RK, Newton-Vinson P, Edmondson DE: Phentermine inhibition of recombinant human liver monoamine oxidases A and B. Biochem Pharmacol. 2002 Mar 1;63(5):865-9. |
| Groups | Approved; Illicit |
| Direct Classification | Amphetamines and derivatives |
| SMILES | CC(C)(N)CC1=CC=CC=C1 |
| Pathways | |
| PharmGKB | PA164748099 |
| ChEMBL | CHEMBL1574 |
