| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10039668 | HBV | ENSG00000055118.18 | protein_coding | KCNH2 | No | No | 3757 | A0A090N7W1 A0A090N7X5 A0A090N8Q0 Q12809 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | KCNH2 |
|---|---|
| DrugBank ID | DB01136 |
| Drug Name | Carvedilol |
| Target ID | BE0000090 |
| UniProt ID | Q12809 |
| Regulation Type | inhibitor |
| PubMed IDs | 11164846; 16314852 |
| Citations | Karle CA, Kreye VA, Thomas D, Rockl K, Kathofer S, Zhang W, Kiehn J: Antiarrhythmic drug carvedilol inhibits HERG potassium channels. Cardiovasc Res. 2001 Feb 1;49(2):361-70.@@Kawakami K, Nagatomo T, Abe H, Kikuchi K, Takemasa H, Anson BD, Delisle BP, January CT, Nakashima Y: Comparison of HERG channel blocking effects of various beta-blockers-- implication for clinical strategy. Br J Pharmacol. 2006 Mar;147(6):642-52. |
| Groups | Approved; Investigational |
| Direct Classification | Carbazoles |
| SMILES | COC1=CC=CC=C1OCCNCC(O)COC1=CC=CC2=C1C1=CC=CC=C1N2 |
| Pathways | Carvedilol Action Pathway |
| PharmGKB | PA448817 |
| ChEMBL | CHEMBL723 |
