| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10039668 | HBV | ENSG00000055118.18 | protein_coding | KCNH2 | No | No | 3757 | A0A090N7W1 A0A090N7X5 A0A090N8Q0 Q12809 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | KCNH2 |
|---|---|
| DrugBank ID | DB11642 |
| Drug Name | Pitolisant |
| Target ID | BE0000090 |
| UniProt ID | Q12809 |
| Regulation Type | blocker |
| PubMed IDs | 28941245 |
| Citations | Ligneau X, Shah RR, Berrebi-Bertrand I, Mirams GR, Robert P, Landais L, Maison-Blanche P, Faivre JF, Lecomte JM, Schwartz JC: Nonclinical cardiovascular safety of pitolisant: comparing International Conference on Harmonization S7B and Comprehensive in vitro Pro-arrhythmia Assay initiative studies. Br J Pharmacol. 2017 Dec;174(23):4449-4463. doi: 10.1111/bph.14047. Epub 2017 Oct 19. |
| Groups | Approved; Investigational |
| Direct Classification | Chlorobenzenes |
| SMILES | ClC1=CC=C(CCCOCCCN2CCCCC2)C=C1 |
| Pathways | |
| PharmGKB | |
| ChEMBL | CHEMBL462605 |
