Gene: SLC27A2

11001
ACSVL1|FACVL1|FATP2|HsT17226|VLACS|VLCS|hFACVL1
solute carrier family 27 member 2
protein-coding
15q21.2
Ensembl:ENSG00000140284 MIM:603247 Vega:OTTHUMG00000131643 UniprotKB:O14975
NC_000015.10
SNP Mapped
1   ANCO-SNPs
AD
0   
NA (AD)  NA (ND)   (Frontal_Cortex)
3.572e-1 (AD)  5.552e-1 (ND)

ANCO-SNPs

SNP ID Position Alleles Trait Variation Type
rs1365507chr15:50185038 (GRCh38.p7)A>Galcohol dependenceSNV(Single Nucleotide Variation)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
FGF140.91
GABRB30.904
ELMOD10.902
CYP4X10.902
PAK30.898
TMEM2460.898
DGKB0.897
TUSC30.897
LRRTM40.897
HTR5A0.896

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
REST-0.567
RAI14-0.556
HEY2-0.546
YES1-0.545
CSAG1-0.527
FZD10-0.523
CHST14-0.519
RNF135-0.519
DOCK1-0.511
WWTR1-0.509

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
C5112952,2',4,4'-tetrabromodiphenyl ether"2,2',4,4'-tetrabromodiphenyl ether results in decreased expression of SLC27A2 mRNA"25614096
C5254852-(2'-hydroxy-3',5'-di-tert-butylphenyl)benzotriazole"2-(2'-hydroxy-3',5'-di-tert-butylphenyl)benzotriazole affects the expression of SLC27A2 mRNA"27665778
C0142112,3,7,8-tetrachlorodibenzofuran"2,3,7,8-tetrachlorodibenzofuran affects the expression of SLC27A2 mRNA"18343893
C0294972,3-bis(3'-hydroxybenzyl)butyrolactone"[Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of SLC27A2 mRNA"19167446
C0140242,4,5,2',4',5'-hexachlorobiphenyl"[Tetrachlorodibenzodioxin co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with Diethylhexyl Phthalate co-treated with bisphenol A] results in increased expression of SLC27A2 mRNA"28433925
C0164032,4-dinitrotoluene"2,4-dinitrotoluene results in decreased expression of SLC27A2 mRNA"24893713
C0235142,6-dinitrotoluene"2,6-dinitrotoluene affects the expression of SLC27A2 mRNA"21346803
C0284513,4,3',4'-tetrachlorobiphenyl"3,4,3',4'-tetrachlorobiphenyl inhibits the reaction [Dietary Fats results in increased expression of SLC27A2 mRNA]"19467301
C0230353,4,5,3',4'-pentachlorobiphenyl"3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SLC27A2 mRNA"23994337
C5756314-(4-(2,4-dioxothiazolidin-5-ylidenemethyl)-2-methoxyphenoxy)-3-trifluoromethylbenzonitrile"4-(4-(2,4-dioxothiazolidin-5-ylidenemethyl)-2-methoxyphenoxy)-3-trifluoromethylbenzonitrile affects the expression of SLC27A2 mRNA"21218783
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with belinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of SLC27A2 mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with mercuric bromide co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SLC27A2 mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with panobinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of SLC27A2 mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SLC27A2 mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with vorinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of SLC27A2 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with belinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of SLC27A2 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with mercuric bromide co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SLC27A2 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with panobinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of SLC27A2 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SLC27A2 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with vorinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of SLC27A2 mRNA"27188386
D000082AcetaminophenAcetaminophen affects the expression of SLC27A2 mRNA25704631
D000082AcetaminophenAcetaminophen results in decreased expression of SLC27A2 mRNA26690555|2906747
D000082Acetaminophen[Clofibrate co-treated with Acetaminophen] affects the expression of SLC27A2 mRNA17585979
D000082AcetaminophenPPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of SLC27A2 mRNA]17585979
D000082AcetaminophenAcetaminophen results in decreased expression of SLC27A2 mRNA15120968
D000111Acetylcysteine[Acetylcysteine co-treated with Dietary Fats] results in increased expression of SLC27A2 mRNA21051528
C106812adefovir dipivoxiladefovir dipivoxil results in decreased expression of SLC27A2 mRNA25596134
D016604Aflatoxin B1Aflatoxin B1 affects the expression of SLC27A2 protein20106945
D016604Aflatoxin B1Aflatoxin B1 results in decreased expression of SLC27A2 mRNA19770486
D000517alpha-Chlorohydrinalpha-Chlorohydrin results in increased expression of SLC27A2 mRNA28522335
D000638AmiodaroneAmiodarone affects the expression of SLC27A2 mRNA19483382
D000643Ammonium ChlorideAmmonium Chloride affects the expression of SLC27A2 mRNA16483693
D018501Antirheumatic AgentsAntirheumatic Agents results in decreased expression of SLC27A2 mRNA24449571
C006632arsenic trioxidearsenic trioxide results in increased expression of SLC27A2 mRNA22521957
C487081belinostat"[NOG protein co-treated with belinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of SLC27A2 mRNA"27188386
D001553BenzbromaroneBenzbromarone affects the expression of SLC27A2 mRNA19483382
D019324beta-Naphthoflavonebeta-Naphthoflavone results in increased expression of SLC27A2 mRNA23994337
D001564Benzo(a)pyreneBenzo(a)pyrene promotes the reaction [AHR protein binds to SLC27A2 promoter]19654925
D0151237,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide"7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of SLC27A2 mRNA"19150397
D004958EstradiolEstradiol affects the expression of SLC27A2 mRNA14699072
D004958EstradiolEstradiol results in increased expression of SLC27A2 mRNA21185374
D004958Estradiol[Estradiol co-treated with Progesterone] results in decreased expression of SLC27A2 mRNA19693291
C095105bexarotenebexarotene results in decreased expression of SLC27A2 mRNA16648578
D001629BezafibrateBezafibrate inhibits the reaction [SLC27A2 gene mutant form results in decreased expression of ACADM mRNA]11929713
D001629BezafibrateBezafibrate results in increased expression of SLC27A2 mRNA17118139|1912461
D001629BezafibratePPARA protein affects the susceptibility to [Bezafibrate results in increased expression of SLC27A2 mRNA]19124612
C006780bisphenol Abisphenol A affects the expression of SLC27A2 mRNA21786754
C006780bisphenol Abisphenol A affects the methylation of SLC27A2 promoter27334623
C006780bisphenol Abisphenol A results in decreased expression of SLC27A2 mRNA21932408
C006780bisphenol A"[Tetrachlorodibenzodioxin co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with Diethylhexyl Phthalate co-treated with bisphenol A] results in increased expression of SLC27A2 mRNA"28433925
C006780bisphenol Abisphenol A results in increased expression of SLC27A2 mRNA25181051
C006780bisphenol Abisphenol A results in increased methylation of SLC27A2 gene28505145
D0151248-Bromo Cyclic Adenosine Monophosphate8-Bromo Cyclic Adenosine Monophosphate results in increased expression of SLC27A2 mRNA22079614
D020122tert-Butylhydroperoxidetert-Butylhydroperoxide affects the expression of SLC27A2 mRNA23410634
C584509C646 compoundC646 compound results in increased expression of SLC27A2 mRNA26191083
D019256Cadmium ChlorideCadmium Chloride results in decreased expression of SLC27A2 mRNA25596134
D019256Cadmium Chloride[Cadmium Chloride co-treated with methylmercuric chloride] results in increased expression of SLC27A2 mRNA27814245
D019256Cadmium ChlorideCadmium Chloride results in increased expression of SLC27A2 mRNA26352046
D002251Carbon TetrachlorideCarbon Tetrachloride affects the expression of SLC27A2 mRNA15963342
C004656chloroacetaldehydechloroacetaldehyde results in decreased expression of SLC27A2 mRNA25596134
D020245p-Chloromercuribenzoic Acid"[NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SLC27A2 mRNA"27188386
D020245p-Chloromercuribenzoic Acidp-Chloromercuribenzoic Acid results in increased expression of SLC27A2 mRNA26272509
C074702chromium hexavalent ionchromium hexavalent ion affects the expression of SLC27A2 mRNA28472532
C059262cidofovircidofovir results in decreased expression of SLC27A2 mRNA25596134
D002922CiguatoxinsCiguatoxins affects the expression of SLC27A2 mRNA18353800
D002994Clofibrate[Clofibrate co-treated with Acetaminophen] affects the expression of SLC27A2 mRNA17585979
D002994ClofibrateClofibrate results in increased expression of SLC27A2 mRNA17585979
D002994ClofibratePPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of SLC27A2 mRNA]17585979
D002994ClofibrateClofibrate affects the expression of SLC27A2 mRNA19483382|2766577
D002995Clofibric Acid[Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of SLC27A2 mRNA17602206
C018021cobaltous chloridecobaltous chloride results in decreased expression of SLC27A2 mRNA19376846
C018021cobaltous chloridecobaltous chloride results in decreased expression of SLC27A2 mRNA24386269
D003300Copper[NSC 689534 binds to Copper] which results in decreased expression of SLC27A2 mRNA20971185
D019327Copper SulfateCopper Sulfate results in decreased expression of SLC27A2 mRNA19549813
C030123coumarincoumarin affects the expression of SLC27A2 mRNA16963487
D003375Coumestrol"[Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of SLC27A2 mRNA"19167446
D003375Coumestrol[Coumestrol co-treated with resveratrol] results in increased expression of SLC27A2 mRNA19167446
D003375CoumestrolCoumestrol results in increased expression of SLC27A2 mRNA19167446
C030973cupric oxidecupric oxide results in decreased expression of SLC27A2 mRNA22077320
D003471CuprizoneCuprizone results in decreased expression of SLC27A2 mRNA26577399
D016572CyclosporineCyclosporine results in decreased expression of SLC27A2 mRNA20106945|2490755
D016572CyclosporineCyclosporine results in decreased expression of SLC27A2 mRNA19770486
D003840Deoxycholic AcidDeoxycholic Acid inhibits the reaction [SLC27A2 protein results in increased uptake of Fatty Acids]22531947
D003907DexamethasoneDexamethasone affects the expression of SLC27A2 mRNA15102944
C000944dicrotophosdicrotophos results in decreased expression of SLC27A2 mRNA28302478
D004041Dietary Fats"3,4,3',4'-tetrachlorobiphenyl inhibits the reaction [Dietary Fats results in increased expression of SLC27A2 mRNA]"19467301
D004041Dietary FatsDietary Fats results in increased expression of SLC27A2 mRNA19467301
D004041Dietary Fats[Acetylcysteine co-treated with Dietary Fats] results in increased expression of SLC27A2 mRNA21051528
D004041Dietary Fats[Ethanol co-treated with Dietary Fats] results in increased expression of SLC27A2 mRNA21051528
D004051Diethylhexyl Phthalate"[Tetrachlorodibenzodioxin co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with Diethylhexyl Phthalate co-treated with bisphenol A] results in increased expression of SLC27A2 mRNA"28433925
D004052Diethylnitrosamine[Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of SLC27A2 mRNA17602206
D002117CalcitriolCalcitriol results in increased expression of SLC27A2 mRNA27107558
D052244Endocrine DisruptorsEndocrine Disruptors results in increased expression of SLC27A2 mRNA25198161
C045651epigallocatechin gallate[potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of SLC27A2 mRNA22079256
D004917Erythromycin[Penicillin G co-treated with Erythromycin] results in increased expression of SLC27A2 mRNA27503388
D000431Ethanol[Ethanol co-treated with Dietary Fats] results in increased expression of SLC27A2 mRNA21051528
D005001EthionineEthionine affects the expression of SLC27A2 mRNA19483382
C098546ethyl tert-butyl etherethyl tert-butyl ether results in increased expression of SLC27A2 protein24090815
D005227Fatty AcidsDeoxycholic Acid inhibits the reaction [SLC27A2 protein results in increased uptake of Fatty Acids]22531947
D005227Fatty AcidsSLC27A2 protein results in increased uptake of Fatty Acids22531947
D011345FenofibrateFenofibrate results in increased expression of SLC27A2 mRNA25572481
D011345FenofibrateFenofibrate results in increased expression of SLC27A2 mRNA17118139
D011345FenofibrateFenofibrate results in increased expression of SLC27A2 mRNA27665778
D005485FlutamideFlutamide results in decreased expression of SLC27A2 mRNA24793618
D005632FructoseFructose results in decreased expression of SLC27A2 protein28257781
C056933fumonisin B1fumonisin B1 results in decreased expression of SLC27A2 mRNA16221962
C039281furanfuran results in decreased expression of SLC27A2 mRNA15120968
C039281furanfuran results in increased methylation of SLC27A2 gene22079235
D015248GemfibrozilGemfibrozil affects the expression of SLC27A2 mRNA27665778
D017313FenretinideFenretinide results in increased expression of SLC27A2 mRNA28973697
D006861Hydrogen PeroxideHydrogen Peroxide affects the expression of SLC27A2 mRNA23410634
C492448ICG 001ICG 001 results in increased expression of SLC27A2 mRNA26191083
C075954indolo(3,2-b)carbazole"indolo(3,2-b)carbazole results in increased expression of SLC27A2 mRNA"23994337
D015759Ionomycin[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of SLC27A2 mRNA25613284
C544151jinfukangjinfukang results in decreased expression of SLC27A2 mRNA27392435
C099406L 742694L 742694 affects the expression of SLC27A2 mRNA15102944
C042720mercuric bromide"[NOG protein co-treated with mercuric bromide co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SLC27A2 mRNA"27188386
D008727MethotrexateMethotrexate results in increased expression of SLC27A2 mRNA17400583
D008727MethotrexateSLC27A2 protein affects the susceptibility to Methotrexate16217747
D008727MethotrexateMethotrexate affects the expression of SLC27A2 mRNA18502557
C004925methylmercuric chloride[Cadmium Chloride co-treated with methylmercuric chloride] results in increased expression of SLC27A2 mRNA27814245
C500085muraglitazarmuraglitazar results in increased expression of SLC27A2 mRNA21515302
D009525NiacinNiacin results in increased expression of SLC27A2 mRNA24767308
C558013NSC 689534[NSC 689534 binds to Copper] which results in decreased expression of SLC27A2 mRNA20971185
D009853OmeprazoleOmeprazole affects the expression of SLC27A2 mRNA19483382
D010100OxygenOxygen deficiency results in decreased expression of SLC27A2 mRNA25596134
C496932panobinostat"[NOG protein co-treated with panobinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of SLC27A2 mRNA"27188386
D010400Penicillin G[Penicillin G co-treated with Erythromycin] results in increased expression of SLC27A2 mRNA27503388
C471071perfluorohexanesulfonic acidperfluorohexanesulfonic acid results in increased expression of SLC27A2 mRNA21705711
C076994perfluorooctane sulfonic acidperfluorooctane sulfonic acid affects the expression of SLC27A2 mRNA19429403
C076994perfluorooctane sulfonic acidperfluorooctane sulfonic acid results in increased expression of SLC27A2 mRNA20936131|2170571
C076994perfluorooctane sulfonic acidperfluorooctane sulfonic acid results in increased expression of SLC27A2 mRNA18692542|1916217
C023036perfluorooctanoic acidperfluorooctanoic acid affects the expression of SLC27A2 mRNA19429403
C023036perfluorooctanoic acidperfluorooctanoic acid results in increased expression of SLC27A2 mRNA17681415|1846767
C023036perfluorooctanoic acidPPARA protein promotes the reaction [perfluorooctanoic acid results in increased expression of SLC27A2 mRNA]18467677
C023036perfluorooctanoic acidperfluorooctanoic acid results in increased expression of SLC27A2 mRNA28511854
D010634PhenobarbitalPhenobarbital affects the expression of SLC27A2 mRNA19084549
C006253pirinixic acid[pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of SLC27A2 mRNA18489776
C006253pirinixic acidpirinixic acid results in increased expression of SLC27A2 mRNA15777286|1622196
C006253pirinixic acidPPARA protein affects the reaction [pirinixic acid results in increased expression of SLC27A2 mRNA]15777286
C006253pirinixic acidpirinixic acid affects the expression of SLC27A2 mRNA19483382
C006253pirinixic acidpirinixic acid results in increased expression of SLC27A2 mRNA19162173|2766577
C027373potassium chromate(VI)[potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of SLC27A2 mRNA22079256
C027373potassium chromate(VI)potassium chromate(VI) results in decreased expression of SLC27A2 mRNA22079256
C027373potassium chromate(VI)potassium chromate(VI) results in increased expression of SLC27A2 mRNA22714537
D011192Potassium DichromatePotassium Dichromate results in decreased expression of SLC27A2 mRNA23608068
D017035PravastatinPravastatin results in decreased expression of SLC27A2 mRNA27225895
D017035PravastatinPravastatin results in decreased expression of SLC27A2 mRNA27225895
D011374ProgesteroneProgesterone results in increased expression of SLC27A2 mRNA23012394
D011374Progesterone[Estradiol co-treated with Progesterone] results in decreased expression of SLC27A2 mRNA19693291
D011441PropylthiouracilPropylthiouracil affects the expression of SLC27A2 mRNA19483382
D011441PropylthiouracilPropylthiouracil results in increased expression of SLC27A2 mRNA24780913
D011794QuercetinQuercetin results in decreased expression of SLC27A2 mRNA21632981
C059514resveratrol[Coumestrol co-treated with resveratrol] results in increased expression of SLC27A2 mRNA19167446
D015474IsotretinoinIsotretinoin results in decreased expression of SLC27A2 mRNA20436886
D012293RifampinRifampin results in increased expression of SLC27A2 mRNA27199754
C089730rosiglitazonerosiglitazone results in decreased expression of SLC27A2 mRNA25596134
C089730rosiglitazonerosiglitazone results in increased expression of SLC27A2 mRNA25572481
C089730rosiglitazonerosiglitazone results in increased expression of SLC27A2 mRNA21515302
D012906SmokeSmoke results in decreased expression of SLC27A2 mRNA21095227
C009277sodium arsenatesodium arsenate results in decreased expression of SLC27A2 mRNA23922661
C016104sodium bichromatesodium bichromate results in decreased expression of SLC27A2 mRNA22561333
C031655tauroursodeoxycholic acidtauroursodeoxycholic acid results in decreased expression of SLC27A2 mRNA15885361
C501413tesaglitazartesaglitazar results in increased expression of SLC27A2 mRNA21515302
D013739TestosteroneTestosterone results in increased expression of SLC27A2 mRNA19693291
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in decreased expression of SLC27A2 mRNA21998131
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of SLC27A2 mRNA22903824
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the expression of SLC27A2 mRNA18343893|2637764
D013749Tetrachlorodibenzodioxin"[Tetrachlorodibenzodioxin co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with Diethylhexyl Phthalate co-treated with bisphenol A] results in increased expression of SLC27A2 mRNA"28433925
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in decreased expression of SLC27A2 mRNA19770486
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of SLC27A2 mRNA15800033|1661135
D013750TetrachloroethyleneTetrachloroethylene results in increased expression of SLC27A2 mRNA28973375
D013752TetracyclineTetracycline results in decreased expression of SLC27A2 mRNA24489787
D013755Tetradecanoylphorbol Acetate[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of SLC27A2 mRNA25613284
D013853ThioacetamideThioacetamide affects the expression of SLC27A2 mRNA19483382
D014212TretinoinTretinoin results in decreased expression of SLC27A2 mRNA23724009
D014241TrichloroethyleneTrichloroethylene results in increased expression of SLC27A2 mRNA28973375
C012589trichostatin Atrichostatin A results in increased expression of SLC27A2 mRNA24935251
C057693troglitazonetroglitazone results in increased expression of SLC27A2 mRNA21515302
D014635Valproic AcidValproic Acid results in increased expression of SLC27A2 mRNA23179753|2800136
D014635Valproic AcidValproic Acid affects the expression of SLC27A2 mRNA17292431
D014635Valproic AcidValproic Acid results in decreased expression of SLC27A2 mRNA24896083
D014638VanadatesVanadates results in decreased expression of SLC27A2 mRNA22714537
D001335Vehicle EmissionsVehicle Emissions results in increased methylation of SLC27A2 gene25560391
D024483Vitamin K 3Vitamin K 3 affects the expression of SLC27A2 mRNA20044591|2341063
C111237vorinostat"[NOG protein co-treated with vorinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of SLC27A2 mRNA"27188386
D014874Water Pollutants, Chemical"Water Pollutants, Chemical results in increased expression of SLC27A2 mRNA"25198161
D015215ZidovudineZidovudine results in increased expression of SLC27A2 mRNA24292225
C088658zoledronic acidzoledronic acid results in decreased expression of SLC27A2 mRNA24714768|2559613
C088658zoledronic acidzoledronic acid results in increased expression of SLC27A2 mRNA28871336
C088658zoledronic acidzoledronic acid results in increased expression of SLC27A2 protein28871336
C088658zoledronic acidSLC27A2 gene mutant form inhibits the reaction [zoledronic acid results in decreased expression of ACOX1 mRNA]28871336
C088658zoledronic acidSLC27A2 gene mutant form inhibits the reaction [zoledronic acid results in decreased expression of ACOX2 mRNA]28871336
C088658zoledronic acidSLC27A2 gene mutant form inhibits the reaction [zoledronic acid results in decreased expression of CPT1A mRNA]28871336
C088658zoledronic acidSLC27A2 gene mutant form inhibits the reaction [zoledronic acid results in decreased expression of CPT2 mRNA]28871336
C088658zoledronic acidSLC27A2 gene mutant form inhibits the reaction [zoledronic acid results in decreased expression of PPARA mRNA]28871336
C088658zoledronic acidSLC27A2 gene mutant form inhibits the reaction [zoledronic acid results in decreased expression of PPARGC1A mRNA]28871336
C088658zoledronic acidSLC27A2 gene mutant form inhibits the reaction [zoledronic acid results in increased expression of ACTA2 protein]28871336
C088658zoledronic acidSLC27A2 gene mutant form inhibits the reaction [zoledronic acid results in increased expression of COL1A1 mRNA]28871336
C088658zoledronic acidSLC27A2 gene mutant form inhibits the reaction [zoledronic acid results in increased expression of COL3A1 mRNA]28871336
C088658zoledronic acidSLC27A2 gene mutant form inhibits the reaction [zoledronic acid results in increased expression of COL4A1 mRNA]28871336
C088658zoledronic acidSLC27A2 gene mutant form inhibits the reaction [zoledronic acid results in increased expression of FN1 mRNA]28871336
C088658zoledronic acidSLC27A2 gene mutant form inhibits the reaction [zoledronic acid results in increased expression of FN1 protein]28871336
C088658zoledronic acidSLC27A2 gene mutant form inhibits the reaction [zoledronic acid results in increased expression of IL6 mRNA]28871336
C088658zoledronic acidSLC27A2 gene mutant form inhibits the reaction [zoledronic acid results in increased expression of TIMP1 mRNA]28871336
C088658zoledronic acidSLC27A2 gene mutant form inhibits the reaction [zoledronic acid results in increased expression of TIMP2 mRNA]28871336
C088658zoledronic acidSLC27A2 gene mutant form inhibits the reaction [zoledronic acid results in increased expression of TNF mRNA]28871336
C088658zoledronic acidSLC27A2 gene mutant form inhibits the reaction [zoledronic acid results in increased expression of VIM mRNA]28871336
C088658zoledronic acidzoledronic acid results in increased expression of SLC27A2 mRNA28871336
C088658zoledronic acidzoledronic acid results in increased expression of SLC27A2 protein28871336

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0004467long-chain fatty acid-CoA ligase activity-IDA10198260  22022213  
GO:0004467long-chain fatty acid-CoA ligase activity-TAS-  
GO:0005102signaling receptor binding-IPI20178365  
GO:0005524ATP binding-IEA-  
GO:0015245fatty acid transmembrane transporter activity-IEA-  
GO:0019899enzyme binding-IPI16781659  
GO:0031957very long-chain fatty acid-CoA ligase activity-IDA10198260  11980911  
GO:0050197phytanate-CoA ligase activity-IDA10198260  
GO:0050197phytanate-CoA ligase activity-TAS-  
GO:0070251pristanate-CoA ligase activity-IDA10198260  
GO:0070251pristanate-CoA ligase activity-TAS-  
GO:0102391decanoate-CoA ligase activity-IEA-  
GO ID GO Term Qualifier Evidence PubMed
GO:0001561fatty acid alpha-oxidation-IDA10198260  
GO:0001561fatty acid alpha-oxidation-TAS-  
GO:0001676long-chain fatty acid metabolic process-IDA22022213  
GO:0006625protein targeting to peroxisome-TAS-  
GO:0006635fatty acid beta-oxidation-IDA10198260  
GO:0006699bile acid biosynthetic process-IDA11980911  
GO:0006699bile acid biosynthetic process-TAS-  
GO:0042760very long-chain fatty acid catabolic process-IEA-  
GO:0043312neutrophil degranulation-TAS-  
GO:0044539long-chain fatty acid import-IDA22022213  
GO:0097089methyl-branched fatty acid metabolic process-IDA10198260  
GO ID GO Term Qualifier Evidence PubMed
GO:0005778peroxisomal membrane-IDA10640429  
GO:0005778peroxisomal membrane-TAS-  
GO:0005779integral component of peroxisomal membrane-IDA10198260  
GO:0005788endoplasmic reticulum lumen-IDA10198260  
GO:0005789endoplasmic reticulum membrane-IDA22022213  
GO:0005789endoplasmic reticulum membrane-TAS-  
GO:0005829cytosol-TAS-  
GO:0005886plasma membrane-TAS-  
GO:0030176integral component of endoplasmic reticulum membrane-IDA11980911  
GO:0035579specific granule membrane-TAS-  
GO:0070062extracellular exosome-HDA19056867  
KEGG ID KEGG Term
hsa03320PPAR signaling pathway
hsa04146Peroxisome
Reactome ID Reactome Term Evidence
R-HSA-1430728MetabolismTAS
R-HSA-168249Innate Immune SystemTAS
R-HSA-168256Immune SystemTAS
R-HSA-192105Synthesis of bile acids and bile saltsTAS
R-HSA-193368Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterolTAS
R-HSA-193775Synthesis of bile acids and bile salts via 24-hydroxycholesterolTAS
R-HSA-194068Bile acid and bile salt metabolismTAS
R-HSA-389599Alpha-oxidation of phytanateTAS
R-HSA-390918Peroxisomal lipid metabolismTAS
R-HSA-392499Metabolism of proteinsTAS
R-HSA-392499Metabolism of proteinsIEA
R-HSA-556833Metabolism of lipidsTAS
R-HSA-6798695Neutrophil degranulationTAS
R-HSA-8957322Metabolism of steroidsTAS
R-HSA-8978868Fatty acid metabolismTAS
R-HSA-9033241Peroxisomal protein importTAS
R-HSA-9033241Peroxisomal protein importIEA

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal