Gene: SPINDOC

144097
C11orf84|SPIN-DOC
spindlin interactor and repressor of chromatin binding
protein-coding
11q13.1
Ensembl:ENSG00000168005 Vega:OTTHUMG00000167746 UniprotKB:Q9BUA3
NC_000011.10
SNP Mapped
1   ANCO-SNPs
AD
0   
NA (AD)  NA (ND)   (Frontal_Cortex)
2.352e-1 (AD)  6.933e-1 (ND)

ANCO-SNPs

SNP ID Position Alleles Trait Variation Type
rs10897449chr11:63825149 (GRCh38.p7)C>Talcohol dependenceSNV(Single Nucleotide Variation)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
D000082AcetaminophenAcetaminophen results in increased expression of SPINDOC mRNA22230336
D020106AcrylamideAcrylamide results in increased expression of SPINDOC mRNA28959563
C006780bisphenol Abisphenol A results in decreased expression of SPINDOC mRNA25181051
C584509C646 compoundC646 compound results in decreased expression of SPINDOC mRNA26191083
D003471CuprizoneCuprizone results in decreased expression of SPINDOC mRNA26577399
D007854LeadLead affects the expression of SPINDOC mRNA28903495
C568608PCI 5002[PCI 5002 co-treated with Zinc] results in increased expression of SPINDOC mRNA18593933
D011441PropylthiouracilPropylthiouracil results in increased expression of SPINDOC mRNA24780913
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the expression of SPINDOC mRNA22298810
D014028Tobacco Smoke PollutionTobacco Smoke Pollution results in increased expression of SPINDOC mRNA28065790
D014635Valproic AcidValproic Acid affects the expression of SPINDOC mRNA25979313
D014635Valproic AcidValproic Acid results in decreased expression of SPINDOC mRNA23179753
D015032Zinc[PCI 5002 co-treated with Zinc] results in increased expression of SPINDOC mRNA18593933

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0005515protein binding-IPI29061846  
GO ID GO Term Qualifier Evidence PubMed
GO:0006351transcription, DNA-templated-IEA-  
GO:0045892negative regulation of transcription, DNA-templated-IBA21873635  
GO:0045892negative regulation of transcription, DNA-templated-IDA29061846  
GO ID GO Term Qualifier Evidence PubMed
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal