Gene: ZNF804B

219578
-
zinc finger protein 804B
protein-coding
7q21.13
Ensembl:ENSG00000182348 Vega:OTTHUMG00000131037 UniprotKB:A4D1E1
NC_000007.14
SNP Mapped
1   ANCO-SNPs
AD
0   
NA (AD)  NA (ND)   (Frontal_Cortex)
2.426e-1 (AD)  9.213e-2 (ND)

ANCO-SNPs

SNP ID Position Alleles Trait Variation Type
rs17165697chr7:88951002 (GRCh38.p7)G>Aalcohol dependenceSNV(Single Nucleotide Variation)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
COL19A10.742
KCNH70.734
GRM50.723
TRPC50.723
CNTNAP50.72
SYT100.708
CDKL50.702
PCDHAC10.701
NYAP20.689
GABRG30.685

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
IMPA2-0.46
AGTRAP-0.436
ROM1-0.435
RAB13-0.433
NBPF10-0.43
PLIN2-0.425
TGIF1-0.424
MT1M-0.417
RAB20-0.413
GNG5-0.413

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
C0396742,3,4,5-tetrachlorophenate"ZNF804B gene SNP affects the susceptibility to 2,3,4,5-tetrachlorophenate"25622337
D016604Aflatoxin B1Aflatoxin B1 results in decreased methylation of ZNF804B gene27153756
C547126AZM551248AZM551248 results in increased expression of ZNF804B mRNA22323515
D014635Valproic AcidValproic Acid results in decreased methylation of ZNF804B gene29154799
D015034Zinc OxideZinc Oxide analog results in decreased expression of ZNF804B mRNA27215404

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0003676nucleic acid binding-IEA-  
GO:0046872metal ion binding-IEA-  
GO ID GO Term Qualifier Evidence PubMed
GO ID GO Term Qualifier Evidence PubMed
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence
R-HSA-212436Generic Transcription PathwayTAS
R-HSA-73857RNA Polymerase II TranscriptionTAS
R-HSA-74160Gene expression (Transcription)TAS

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal