Gene: ZNF292

23036
Nbla00365|ZFP292|ZN-16|Zn-15|bA393I2.3
zinc finger protein 292
protein-coding
6q14.3
Ensembl:ENSG00000188994 MIM:616213 Vega:OTTHUMG00000015164 UniprotKB:O60281
NG_054887.1
SNP Mapped
1   ANCO-SNPs
ND
0   
NA (AD)  NA (ND)   (Frontal_Cortex)
4.262e-1 (AD)  2.443e-1 (ND)

ANCO-SNPs

SNP ID Position Alleles Trait Variation Type
rs3857487chr6:87253970 (GRCh38.p7)A>Gnicotine dependenceSNV(Single Nucleotide Variation)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
DMXL10.907
SNX130.896
MON20.885
LTN10.88
TRIM330.878
NCOA20.875
TAOK10.874
PIKFYVE0.872
CHD90.865
ARID4A0.863

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
OR4F5-0.526
OR4F29-0.487
CSAG1-0.352
MTRNR2L10-0.295
MTRNR2L8-0.286
MTRNR2L9-0.284
MTRNR2L6-0.281
CDC42EP5-0.278
MTRNR2L2-0.271
RNF223-0.26

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
C0294972,3-bis(3'-hydroxybenzyl)butyrolactone"[Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of ZNF292 mRNA"19167446
C109238acylineacyline results in increased expression of ZNF292 mRNA17510436
D000393Air PollutantsAir Pollutants analog results in decreased expression of ZNF292 mRNA21757418
D000535Aluminum[APP protein modified form binds to Aluminum] which results in increased expression of ZNF292 mRNA21298039
D001280AtrazineAtrazine results in decreased expression of ZNF292 mRNA25929836
D0151237,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide"7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of ZNF292 mRNA"20018196|2038263
C006780bisphenol Abisphenol A results in increased expression of ZNF292 mRNA25181051
C000611646bisphenol F[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of ZNF292 mRNA28628672
C018475butyraldehydebutyraldehyde results in decreased expression of ZNF292 mRNA26079696
D002737ChloropreneChloroprene results in increased expression of ZNF292 mRNA23125180
D003010ClorgylineClorgyline results in increased expression of ZNF292 mRNA19691856
C018021cobaltous chloridecobaltous chloride results in increased expression of ZNF292 mRNA19376846|2220211
C018021cobaltous chloridezinc chloride inhibits the reaction [cobaltous chloride results in increased expression of ZNF292 mRNA]22202117
D003375Coumestrol"[Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of ZNF292 mRNA"19167446
D003375Coumestrol[Coumestrol co-treated with resveratrol] results in decreased expression of ZNF292 mRNA19167446
D003375CoumestrolCoumestrol results in decreased expression of ZNF292 mRNA19167446
D016572CyclosporineCyclosporine results in decreased expression of ZNF292 mRNA25562108
D003907Dexamethasone[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of ZNF292 mRNA28628672
D003993Dibutyl PhthalateDibutyl Phthalate results in increased expression of ZNF292 mRNA21266533
D005557FormaldehydeFormaldehyde results in decreased expression of ZNF292 mRNA20655997
D005839GentamicinsGentamicins results in increased expression of ZNF292 mRNA22061828
D006861Hydrogen PeroxideHydrogen Peroxide results in decreased expression of ZNF292 mRNA18951874
D007213Indomethacin[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of ZNF292 mRNA28628672
D015759Ionomycin[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of ZNF292 mRNA25613284
D0150561-Methyl-3-isobutylxanthine[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of ZNF292 mRNA28628672
C544151jinfukangjinfukang results in decreased expression of ZNF292 mRNA27392435
C045463leflunomideleflunomide results in increased expression of ZNF292 mRNA28988120
C004925methylmercuric chloridemethylmercuric chloride results in decreased expression of ZNF292 mRNA28001369
D008741Methyl MethanesulfonateMethyl Methanesulfonate results in increased expression of ZNF292 mRNA23649840
C022838nickel chloridenickel chloride results in increased expression of ZNF292 mRNA17312168|2145529
C022838nickel chloridenickel chloride affects the expression of ZNF292 mRNA22110744
C025256nonylphenolnonylphenol results in increased expression of ZNF292 mRNA22982499
C030110oxaliplatin[oxaliplatin co-treated with Topotecan] results in decreased expression of ZNF292 mRNA25729387
D010100OxygenOxygen deficiency results in increased expression of ZNF292 mRNA25596134
C076994perfluorooctane sulfonic acidperfluorooctane sulfonic acid results in decreased expression of ZNF292 mRNA27153767
C006253pirinixic acid[pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of ZNF292 mRNA19710929
D011374ProgesteroneProgesterone results in increased expression of ZNF292 mRNA19690047
C059514resveratrol[Coumestrol co-treated with resveratrol] results in decreased expression of ZNF292 mRNA19167446
D012402RotenoneRotenone results in decreased expression of ZNF292 mRNA19013527
D012834SilverSilver results in increased expression of ZNF292 mRNA26014281
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the expression of ZNF292 mRNA22298810
D013755Tetradecanoylphorbol Acetate[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of ZNF292 mRNA25613284
D019772Topotecan[oxaliplatin co-treated with Topotecan] results in decreased expression of ZNF292 mRNA25729387
D019772TopotecanTopotecan results in decreased expression of ZNF292 mRNA25729387
C011559tributyltintributyltin results in decreased expression of ZNF292 mRNA27614199
C057693troglitazonetroglitazone results in decreased expression of ZNF292 mRNA28973697
D014635Valproic AcidValproic Acid affects the expression of ZNF292 mRNA25979313
D014635Valproic AcidValproic Acid results in decreased expression of ZNF292 mRNA23179753|2493525
C025643vinclozolinvinclozolin results in increased expression of ZNF292 mRNA23034163
C016837zinc chloridezinc chloride inhibits the reaction [cobaltous chloride results in increased expression of ZNF292 mRNA]22202117

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0000981RNA polymerase II transcription factor activity, sequence-specific DNA binding-ISA-  
GO:0001077transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding-IEA-  
GO:0003677DNA binding-IEA-  
GO:0046872metal ion binding-IEA-  
GO ID GO Term Qualifier Evidence PubMed
GO:0006366transcription by RNA polymerase II-IEA-  
GO:0045944positive regulation of transcription by RNA polymerase II-IEA-  
GO ID GO Term Qualifier Evidence PubMed
GO:0005634nucleus-IEA-  
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal