Gene info: ID 23213

Gene: SULF1

GENE ID: 23213

Synonyms: SULF-1

Description: sulfatase 1

Gene type: protein-coding

Location: 8q13.2-q13.3

dbXrefs: Ensembl:ENSG00000137573 MIM:610012 Vega:OTTHUMG00000164466 UniprotKB:Q8IWU6

RefSeq: NG_042849.1

Retrived from: SNP Mapped

SNPs: 1 ANCO-SNPs

Phenotype: AD

# Publications: 0

Sherlock p-value : NA (AD) NA (ND) (Frontal_Cortex)

Pascal p-value : 1.653e-1 (AD) 8.363e-1 (ND)

ANCO-SNPs

SNP ID	Position	Alleles	Trait	Variation Type
rs16936012	chr8:69530638 (GRCh38.p7)	G>A / G>T	alcohol dependence	SNV(Single Nucleotide Variation)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol	Pearson Correlation Coefficient
HTR7	0.758
SAMD5	0.753
LRRC55	0.752
KCNK2	0.743
MREG	0.736
SSTR2	0.734
DPY19L1	0.723
SYNPO2	0.717
CLMP	0.711
PTPRM	0.71

Top 10 negatively co-expressed genes

Gene Symbol	Pearson Correlation Coefficient
RFX2	-0.446
PPP1R3G	-0.44
EYA2	-0.434
PLIN4	-0.432
PLIN5	-0.432
GLI3	-0.423
EMX2	-0.42
EYA1	-0.418
SALL3	-0.414
RAPSN	-0.409

There is no DrugBank record for this gene !

ID	Drug Name	Action	PubMed
C532162	2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine	"[PIK3CA gene mutant form results in increased susceptibility to 2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine] which results in increased expression of SULF1 mRNA"	20453058
C023035	3,4,5,3',4'-pentachlorobiphenyl	"3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SULF1 mRNA"	23196670
C459179	4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide	"[NOG protein co-treated with entinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of SULF1 mRNA"	27188386
C459179	4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide	"[NOG protein co-treated with mercuric bromide co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of SULF1 mRNA"	27188386
C459179	4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide	"[NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of SULF1 mRNA"	27188386
C459179	4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide	"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of SULF1 mRNA"	27188386
C459179	4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide	"[NOG protein co-treated with trichostatin A co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of SULF1 mRNA"	27188386
C459179	4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide	"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of SULF1 mRNA"	27188386
C516138	(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine	"[NOG protein co-treated with entinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of SULF1 mRNA"	27188386
C516138	(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine	"[NOG protein co-treated with mercuric bromide co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of SULF1 mRNA"	27188386
C516138	(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine	"[NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of SULF1 mRNA"	27188386
C516138	(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine	"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of SULF1 mRNA"	27188386
C516138	(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine	"[NOG protein co-treated with trichostatin A co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of SULF1 mRNA"	27188386
C516138	(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine	"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of SULF1 mRNA"	27188386
D020106	Acrylamide	Acrylamide results in decreased expression of SULF1 mRNA	28959563
D016604	Aflatoxin B1	Aflatoxin B1 results in increased methylation of SULF1 gene	27153756
D000643	Ammonium Chloride	Ammonium Chloride affects the expression of SULF1 mRNA	16483693
D001151	Arsenic	Arsenic affects the methylation of SULF1 gene	25304211
C006632	arsenic trioxide	arsenic trioxide results in decreased expression of SULF1 mRNA	15725085\|2670570
D017638	Asbestos, Crocidolite	"Asbestos, Crocidolite results in decreased expression of SULF1 mRNA"	25351596
D001374	Azacitidine	Azacitidine results in decreased expression of SULF1 mRNA	20823114
C030935	benz(a)anthracene	benz(a)anthracene results in decreased expression of SULF1 mRNA	26377693
C022921	benzo(k)fluoranthene	benzo(k)fluoranthene results in decreased expression of SULF1 mRNA	26377693
D001564	Benzo(a)pyrene	Benzo(a)pyrene results in increased expression of SULF1 mRNA	22228805\|2719552
D004958	Estradiol	[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of SULF1 mRNA	20823114
D004958	Estradiol	[Estradiol co-treated with Tetrachlorodibenzodioxin] results in decreased expression of SULF1 mRNA	19619570
D004958	Estradiol	Estradiol results in increased expression of SULF1 mRNA	19619570\|2118537
C543008	bis(4-hydroxyphenyl)sulfone	[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bis(4-hydroxyphenyl)sulfone] results in decreased expression of SULF1 mRNA	28628672
C006780	bisphenol A	bisphenol A affects the expression of SULF1 mRNA	21786754
C006780	bisphenol A	bisphenol A results in increased expression of SULF1 mRNA	29275510
C006780	bisphenol A	bisphenol A results in decreased expression of SULF1 mRNA	25270620
C006780	bisphenol A	[bisphenol A co-treated with Testosterone] results in decreased expression of SULF1 mRNA	26496021
C006780	bisphenol A	bisphenol A results in increased expression of SULF1 mRNA	25181051
C006780	bisphenol A	bisphenol A results in increased expression of SULF1 protein	24552547
C006780	bisphenol A	bisphenol A results in increased methylation of SULF1 gene	28505145
D019256	Cadmium Chloride	Cadmium Chloride results in increased methylation of SULF1 promoter	22457795
D020245	p-Chloromercuribenzoic Acid	"[NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of SULF1 mRNA"	27188386
D020245	p-Chloromercuribenzoic Acid	p-Chloromercuribenzoic Acid results in decreased expression of SULF1 mRNA	26272509
D004390	Chlorpyrifos	Chlorpyrifos results in decreased expression of SULF1 mRNA	18668222
C031180	chrysene	chrysene results in increased expression of SULF1 mRNA	26377693
D003042	Cocaine	Cocaine results in decreased expression of SULF1 mRNA	27899881
D003300	Copper	[Disulfiram binds to Copper] which results in increased expression of SULF1 mRNA	24690739
D003300	Copper	[Disulfiram binds to Copper] which results in increased expression of SULF1 protein	24690739
D003300	Copper	[Disulfiram binds to Copper] which results in increased expression of SULF1 protein	24690739
D003375	Coumestrol	[Coumestrol co-treated with resveratrol] results in increased expression of SULF1 mRNA	19167446
D003474	Curcumin	Curcumin results in increased expression of SULF1 mRNA	21594647
D003474	Curcumin	Curcumin results in increased expression of SULF1 protein	21594647
D003474	Curcumin	Curcumin results in increased expression of SULF1 protein	21594647
C009160	cyclonite	cyclonite results in decreased expression of SULF1 mRNA	25559034
D016572	Cyclosporine	Cyclosporine results in decreased expression of SULF1 mRNA	27989131
D016572	Cyclosporine	Cyclosporine results in increased expression of SULF1 mRNA	20106945
D000069439	Dasatinib	Dasatinib results in increased expression of SULF1 mRNA	20579391
C010902	decabromobiphenyl ether	decabromobiphenyl ether results in increased expression of SULF1 mRNA	23914054
D003907	Dexamethasone	Dexamethasone inhibits the reaction [RX3 gene mutant form affects the expression of SULF1 mRNA]	27941970
D003907	Dexamethasone	Dexamethasone results in decreased expression of SULF1 mRNA	25047013
D003907	Dexamethasone	[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bis(4-hydroxyphenyl)sulfone] results in decreased expression of SULF1 mRNA	28628672
D003907	Dexamethasone	[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin] results in decreased expression of SULF1 mRNA	28628672
D003994	Bucladesine	[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of SULF1 mRNA	20823114
D002945	Cisplatin	SULF1 protein results in increased susceptibility to Cisplatin	17310998
D004051	Diethylhexyl Phthalate	Diethylhexyl Phthalate results in increased expression of SULF1 mRNA	28085963
D004221	Disulfiram	Disulfiram results in increased expression of SULF1 mRNA	20530235
D004221	Disulfiram	[Disulfiram binds to Copper] which results in increased expression of SULF1 mRNA	24690739
D004221	Disulfiram	[Disulfiram binds to Copper] which results in increased expression of SULF1 protein	24690739
D004221	Disulfiram	[Disulfiram binds to Copper] which results in increased expression of SULF1 protein	24690739
C118739	entinostat	entinostat results in decreased expression of SULF1 mRNA	26272509
C118739	entinostat	"[NOG protein co-treated with entinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of SULF1 mRNA"	27188386
D005557	Formaldehyde	Formaldehyde results in increased expression of SULF1 mRNA	28937961
C039281	furan	furan results in increased expression of SULF1 mRNA	27387713
D006493	Heparin	SULF1 protein results in increased chemical synthesis of Heparin	15051888
D006497	Heparitin Sulfate	SULF1 protein inhibits the reaction [Heparitin Sulfate results in increased activity of FGFR1 protein]	15051888
D006497	Heparitin Sulfate	SULF1 protein results in decreased sulfation of Heparitin Sulfate	15051888
D017313	Fenretinide	Fenretinide results in decreased expression of SULF1 mRNA	28973697
C041508	indeno(1,2,3-cd)pyrene	"indeno(1,2,3-cd)pyrene results in decreased expression of SULF1 mRNA"	26377693
D007213	Indomethacin	[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bis(4-hydroxyphenyl)sulfone] results in decreased expression of SULF1 mRNA	28628672
D007213	Indomethacin	[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin] results in decreased expression of SULF1 mRNA	28628672
D015056	1-Methyl-3-isobutylxanthine	[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bis(4-hydroxyphenyl)sulfone] results in decreased expression of SULF1 mRNA	28628672
D015056	1-Methyl-3-isobutylxanthine	[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin] results in decreased expression of SULF1 mRNA	28628672
C008261	lead acetate	lead acetate affects the expression of SULF1 mRNA	22641619
C533894	LG 100815	LG 100815 results in increased expression of SULF1 mRNA	16951191
D017258	Medroxyprogesterone Acetate	[Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in decreased expression of SULF1 mRNA	20823114
C042720	mercuric bromide	mercuric bromide results in decreased expression of SULF1 mRNA	26272509
C042720	mercuric bromide	"[NOG protein co-treated with mercuric bromide co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of SULF1 mRNA"	27188386
D008727	Methotrexate	Methotrexate affects the expression of SULF1 mRNA	18502557
C004925	methylmercuric chloride	methylmercuric chloride results in decreased expression of SULF1 mRNA	23179753\|2627250
D008767	Methylmercury Compounds	Methylmercury Compounds results in decreased expression of SULF1 mRNA	27544571
D008741	Methyl Methanesulfonate	Methyl Methanesulfonate results in decreased expression of SULF1 mRNA	26011545
C500085	muraglitazar	muraglitazar results in decreased expression of SULF1 mRNA	21515302
D037742	Nanotubes, Carbon	"Nanotubes, Carbon analog results in decreased expression of SULF1 mRNA"	25554681
D037742	Nanotubes, Carbon	"Nanotubes, Carbon results in decreased expression of SULF1 mRNA"	25620056
C029938	nickel sulfate	nickel sulfate results in increased expression of SULF1 mRNA	22714537
C062198	octa-2,4,6-trienoic acid	"octa-2,4,6-trienoic acid results in increased expression of SULF1 mRNA"	16951191
D052638	Particulate Matter	Particulate Matter results in decreased expression of SULF1 mRNA	23085030
D010662	Phenylmercuric Acetate	"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of SULF1 mRNA"	27188386
C006253	pirinixic acid	[pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of SULF1 mRNA	19710929
D011192	Potassium Dichromate	Potassium Dichromate results in decreased expression of SULF1 mRNA	23608068
C513428	pyrachlostrobin	pyrachlostrobin results in increased expression of SULF1 mRNA	27029645
C059514	resveratrol	[Coumestrol co-treated with resveratrol] results in increased expression of SULF1 mRNA	19167446
C089730	rosiglitazone	rosiglitazone results in decreased expression of SULF1 mRNA	21515302
C513635	S-2-pentyl-4-pentynoic hydroxamic acid	S-2-pentyl-4-pentynoic hydroxamic acid results in decreased expression of SULF1 mRNA	21427059
D012643	Selenium	Selenium results in decreased expression of SULF1 mRNA	19244175
D012822	Silicon Dioxide	Silicon Dioxide analog results in increased expression of SULF1 mRNA	23806026
D012822	Silicon Dioxide	Silicon Dioxide results in decreased expression of SULF1 mRNA	22300531\|2535159
D012906	Smoke	Smoke results in decreased expression of SULF1 mRNA	21095227
D018038	Sodium Selenite	Sodium Selenite results in decreased expression of SULF1 mRNA	18175754
C501413	tesaglitazar	tesaglitazar results in decreased expression of SULF1 mRNA	21515302
D013739	Testosterone	[bisphenol A co-treated with Testosterone] results in decreased expression of SULF1 mRNA	26496021
D013749	Tetrachlorodibenzodioxin	[Estradiol co-treated with Tetrachlorodibenzodioxin] results in decreased expression of SULF1 mRNA	19619570
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin results in increased expression of SULF1 mRNA	19619570
D013749	Tetrachlorodibenzodioxin	Tetrachlorodibenzodioxin affects the expression of SULF1 mRNA	21570461
D013853	Thioacetamide	Thioacetamide results in decreased expression of SULF1 mRNA	23411599
D013893	Thiram	Thiram results in increased expression of SULF1 mRNA	20530235
D019772	Topotecan	Topotecan results in increased expression of SULF1 mRNA	25729387
D014212	Tretinoin	Tretinoin results in increased expression of SULF1 mRNA	20530235
D014212	Tretinoin	Tretinoin results in decreased expression of SULF1 mRNA	21934132
C032910	triadimefon	triadimefon results in decreased expression of SULF1 mRNA	26705709
C012589	trichostatin A	"[NOG protein co-treated with trichostatin A co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of SULF1 mRNA"	27188386
C012589	trichostatin A	trichostatin A results in decreased expression of SULF1 mRNA	24935251\|2627250
C012589	trichostatin A	trichostatin A results in increased expression of SULF1 mRNA	24935251
C057693	troglitazone	troglitazone results in decreased expression of SULF1 mRNA	21515302
D014635	Valproic Acid	"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of SULF1 mRNA"	27188386
D014635	Valproic Acid	Valproic Acid affects the expression of SULF1 mRNA	25979313
D014635	Valproic Acid	Valproic Acid results in decreased expression of SULF1 mRNA	23179753\|2438349
D014635	Valproic Acid	Valproic Acid results in increased expression of SULF1 mRNA	23179753\|2718838
D014635	Valproic Acid	Valproic Acid results in decreased expression of SULF1 mRNA	21427059
D014635	Valproic Acid	Valproic Acid results in increased expression of SULF1 mRNA	24896083
D014638	Vanadates	Vanadates results in decreased expression of SULF1 mRNA	22714537
D001335	Vehicle Emissions	Vehicle Emissions results in increased methylation of SULF1 gene	25560391
C025643	vinclozolin	vinclozolin results in decreased expression of SULF1 mRNA	22615374\|2303416
D015032	Zinc	Zinc results in increased expression of SULF1 mRNA	17074742
D019287	Zinc Sulfate	Zinc Sulfate results in increased expression of SULF1 mRNA	17074742

GO/Pathway

GO ID	GO Term	Qualifier	Evidence	PubMed
GO:0004065	arylsulfatase activity	-	IDA	12368295
GO:0004065	arylsulfatase activity	-	IMP	19520866
GO:0005509	calcium ion binding	-	IEA	-
GO:0008449	N-acetylglucosamine-6-sulfatase activity	-	IDA	18687675 19666466
GO:0008449	N-acetylglucosamine-6-sulfatase activity	-	IMP	19520866

GO ID	GO Term	Qualifier	Evidence	PubMed
GO:0001822	kidney development	-	ISS	-
GO:0001937	negative regulation of endothelial cell proliferation	-	IDA	16778174
GO:0002063	chondrocyte development	-	ISS	-
GO:0003094	glomerular filtration	-	ISS	-
GO:0006915	apoptotic process	-	IEA	-
GO:0010575	positive regulation of vascular endothelial growth factor production	-	ISS	-
GO:0014846	esophagus smooth muscle contraction	-	ISS	-
GO:0016525	negative regulation of angiogenesis	-	IDA	16778174
GO:0030177	positive regulation of Wnt signaling pathway	-	IDA	19520866
GO:0030201	heparan sulfate proteoglycan metabolic process	-	IDA	18687675 19666466 19822709
GO:0030201	heparan sulfate proteoglycan metabolic process	-	NAS	12368295
GO:0030336	negative regulation of cell migration	-	IMP	21266348
GO:0030513	positive regulation of BMP signaling pathway	-	IMP	20479257
GO:0032836	glomerular basement membrane development	-	ISS	-
GO:0035860	glial cell-derived neurotrophic factor receptor signaling pathway	-	ISS	-
GO:0040036	regulation of fibroblast growth factor receptor signaling pathway	-	IMP	21266348
GO:0040037	negative regulation of fibroblast growth factor receptor signaling pathway	-	IMP	20479257
GO:0040037	negative regulation of fibroblast growth factor receptor signaling pathway	-	ISS	-
GO:0048010	vascular endothelial growth factor receptor signaling pathway	-	IDA	16778174
GO:0048706	embryonic skeletal system development	-	ISS	-
GO:0051216	cartilage development	-	ISS	-
GO:0060348	bone development	-	ISS	-
GO:0060384	innervation	-	ISS	-
GO:0060686	negative regulation of prostatic bud formation	-	ISS	-

GO ID	GO Term	Qualifier	Evidence	PubMed
GO:0005615	extracellular space	-	HDA	22664934
GO:0005615	extracellular space	-	IDA	19666466
GO:0005615	extracellular space	-	NAS	12368295
GO:0005783	endoplasmic reticulum	-	IDA	18687675
GO:0005794	Golgi apparatus	-	ISS	-
GO:0005795	Golgi stack	-	IEA	-
GO:0005886	plasma membrane	-	ISS	-
GO:0009986	cell surface	-	IDA	12368295 18687675 19520866 19666466
GO:0045121	membrane raft	-	IDA	19520866

KEGG ID	KEGG Term

Reactome ID	Reactome Term	Evidence

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID	Title (Year)	Author	Journal