Gene: TMEM131L

23240
KIAA0922
transmembrane 131 like
protein-coding
4q31.3
Ensembl:ENSG00000121210 MIM:616243 Vega:OTTHUMG00000153244 UniprotKB:A2VDJ0
NC_000004.12
SNP Mapped
1   ANCO-SNPs
AD
0   
NA (AD)  NA (ND)   (Frontal_Cortex)
2.646e-1 (AD)  3.854e-1 (ND)

ANCO-SNPs

SNP ID Position Alleles Trait Variation Type
rs2033831chr4:153637999 (GRCh38.p7)A>Galcohol dependenceSNV(Single Nucleotide Variation)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
D000393Air PollutantsAir Pollutants analog results in decreased expression of TMEM131L mRNA21757418
D001280AtrazineAtrazine results in decreased expression of TMEM131L mRNA22378314
D0151237,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide"7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of TMEM131L mRNA"20382639
C006780bisphenol Abisphenol A affects the expression of TMEM131L mRNA25181051
D016572CyclosporineCyclosporine results in increased expression of TMEM131L mRNA25562108
D002945Cisplatin[Cisplatin co-treated with jinfukang] results in decreased expression of TMEM131L mRNA27392435
C045651epigallocatechin gallate[potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of TMEM131L mRNA22079256
C492448ICG 001ICG 001 results in decreased expression of TMEM131L mRNA26191083
D015759Ionomycin[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of TMEM131L mRNA25613284
C544151jinfukang[Cisplatin co-treated with jinfukang] results in decreased expression of TMEM131L mRNA27392435
D008558MelphalanMelphalan results in decreased expression of TMEM131L mRNA22363485
C004925methylmercuric chloridemethylmercuric chloride results in increased expression of TMEM131L mRNA27188386
D009532NickelNickel results in increased expression of TMEM131L mRNA24768652|2558310
D011078Polychlorinated BiphenylsPolychlorinated Biphenyls affects the expression of TMEM131L mRNA21334430
C027373potassium chromate(VI)[potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of TMEM131L mRNA22079256
C027373potassium chromate(VI)potassium chromate(VI) results in decreased expression of TMEM131L mRNA22079256
D011794QuercetinQuercetin results in increased expression of TMEM131L mRNA21632981
C017947sodium arsenitesodium arsenite results in decreased expression of TMEM131L mRNA28595984
D013755Tetradecanoylphorbol Acetate[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of TMEM131L mRNA25613284
D014028Tobacco Smoke PollutionTobacco Smoke Pollution results in decreased expression of TMEM131L mRNA28065790
D014212TretinoinTretinoin results in decreased expression of TMEM131L mRNA21934132
C012589trichostatin Atrichostatin A results in increased expression of TMEM131L mRNA24935251
D014635Valproic AcidValproic Acid results in decreased expression of TMEM131L mRNA24935251

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO ID GO Term Qualifier Evidence PubMed
GO:0002682regulation of immune system process-IBA21873635  
GO:0016055Wnt signaling pathway-IEA-  
GO:0033088negative regulation of immature T cell proliferation in thymus-IMP23690469  
GO:0090090negative regulation of canonical Wnt signaling pathway-IBA21873635  
GO:0090090negative regulation of canonical Wnt signaling pathway-IDA23690469  
GO ID GO Term Qualifier Evidence PubMed
GO:0005737cytoplasm-IDA23690469  
GO:0005783endoplasmic reticulum-IEA-  
GO:0005886plasma membrane-IBA21873635  
GO:0005886plasma membrane-IDA23690469  
GO:0016020membrane-IBA21873635  
GO:0016021integral component of membrane-IEA-  
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal