Gene: WASHC4

23325
KIAA1033|MRT43|SWIP
WASH complex subunit 4
protein-coding
12q23.3
Ensembl:ENSG00000136051 MIM:615748 Vega:OTTHUMG00000169838 UniprotKB:Q2M389
NG_034157.1
SNP Mapped
1   ANCO-SNPs
AD
0   
NA (AD)  NA (ND)   (Frontal_Cortex)
7.970e-1 (AD)  3.028e-1 (ND)

ANCO-SNPs

SNP ID Position Alleles Trait Variation Type
rs10861359chr12:105168213 (GRCh38.p7)C>Aalcohol dependenceSNV(Single Nucleotide Variation)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
D000082AcetaminophenAcetaminophen results in increased expression of WASHC4 mRNA21420995
D000082AcetaminophenWASHC4 gene polymorphism affects the susceptibility to Acetaminophen26104854
D000395Air Pollutants, Occupational"Air Pollutants, Occupational results in decreased expression of WASHC4 mRNA"23195993
C006780bisphenol Abisphenol A results in decreased expression of WASHC4 mRNA25181051
D002737ChloropreneChloroprene results in increased expression of WASHC4 mRNA23125180
D003375CoumestrolCoumestrol results in decreased expression of WASHC4 mRNA19167446
D003471CuprizoneCuprizone affects the expression of WASHC4 mRNA27523638
D003471CuprizoneCuprizone results in decreased expression of WASHC4 mRNA26577399
C009160cyclonitecyclonite results in decreased expression of WASHC4 mRNA25559034
D002945CisplatinCisplatin results in decreased expression of WASHC4 mRNA27392435
C000944dicrotophosdicrotophos results in decreased expression of WASHC4 mRNA28302478
C045651epigallocatechin gallate[potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of WASHC4 mRNA22079256
C069837fullerene C60fullerene C60 results in increased expression of WASHC4 mRNA19167457
D005897GlafenineGlafenine results in decreased expression of WASHC4 mRNA24136188
D015759Ionomycin[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of WASHC4 mRNA25613284
C544151jinfukangjinfukang results in decreased expression of WASHC4 mRNA27392435
C561695(+)-JQ1 compound(+)-JQ1 compound results in increased expression of WASHC4 mRNA24796395
C410337K 7174K 7174 results in increased expression of WASHC4 mRNA24086573
D009532NickelNickel results in decreased expression of WASHC4 mRNA23195993
C012655nimesulidenimesulide results in increased expression of WASHC4 mRNA24136188
C076994perfluorooctane sulfonic acidperfluorooctane sulfonic acid results in decreased expression of WASHC4 mRNA27153767
D010936Plant ExtractsPlant Extracts results in increased expression of WASHC4 mRNA23557933
C027373potassium chromate(VI)[potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of WASHC4 mRNA22079256
C027373potassium chromate(VI)potassium chromate(VI) results in decreased expression of WASHC4 mRNA22079256
C004648testosterone enanthatetestosterone enanthate affects the expression of WASHC4 mRNA17440010
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the expression of WASHC4 mRNA22298810
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of WASHC4 mRNA20106945|2163298
D013755Tetradecanoylphorbol Acetate[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of WASHC4 mRNA25613284
C057693troglitazonetroglitazone results in decreased expression of WASHC4 mRNA28973697
C025643vinclozolinvinclozolin affects the expression of WASHC4 mRNA19015723
C025643vinclozolinvinclozolin results in decreased expression of WASHC4 mRNA23034163
C025643vinclozolinvinclozolin results in increased expression of WASHC4 mRNA23555832

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO ID GO Term Qualifier Evidence PubMed
GO:0007032endosome organization-IBA21873635  
GO:0007032endosome organization-IMP23676666  
GO:0015031protein transport-IEA-  
GO:0016197endosomal transport-IBA21873635  
GO:0016197endosomal transport-IMP20923837  
GO:0016197endosomal transport-ISS-  
GO ID GO Term Qualifier Evidence PubMed
GO:0005654nucleoplasm-IDA-  
GO:0005768endosome-IBA21873635  
GO:0005768endosome-IDA20923837  
GO:0005769early endosome-IEA-  
GO:0031083BLOC-1 complexcolocalizes_withIDA23676666  
GO:0071203WASH complex-IBA21873635  
GO:0071203WASH complex-IDA19922875  
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal