Gene: ATRNL1

26033
ALP|bA338L11.1|bA454H24.1
attractin like 1
protein-coding
10q25.3
Ensembl:ENSG00000107518 MIM:612869 Vega:OTTHUMG00000019096 UniprotKB:Q5VV63
NC_000010.11
SNP Mapped
1   ANCO-SNPs
ND
0   
NA (AD)  NA (ND)   (Frontal_Cortex)
1.495e-1 (AD)  5.678e-1 (ND)

ANCO-SNPs

SNP ID Position Alleles Trait Variation Type
rs2615891chr10:115880805 (GRCh38.p7)G>Anicotine dependenceSNV(Single Nucleotide Variation)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
DLGAP10.975
AAK10.974
GABRB20.971
KIAA1549L0.971
HCN10.971
SLC4A100.97
MYT1L0.968
GABRA10.968
FRMPD40.967
CNTNAP20.967

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
HEY2-0.576
CSAG1-0.563
RAB13-0.56
MYL3-0.548
RNF135-0.538
AGTRAP-0.536
YES1-0.532
CHST14-0.531
RAI14-0.529
ROM1-0.529

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ATRNL1 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ATRNL1 mRNA"27188386
D020106AcrylamideAcrylamide results in decreased expression of ATRNL1 mRNA28959563
D001280AtrazineAtrazine results in decreased expression of ATRNL1 mRNA25929836
D001280AtrazineAtrazine results in decreased expression of ATRNL1 mRNA22378314
C447119bazedoxifenebazedoxifene results in decreased expression of ATRNL1 mRNA19914376
D001564Benzo(a)pyreneBenzo(a)pyrene results in decreased expression of ATRNL1 mRNA19770486|2171566
D004958Estradiol[Estradiol co-treated with Tetrachlorodibenzodioxin] results in decreased expression of ATRNL1 mRNA19619570
D004958EstradiolEstradiol results in increased expression of ATRNL1 mRNA19619570
D004958EstradiolEstradiol results in decreased expression of ATRNL1 mRNA19484750
D004958Estradiol[bisphenol A co-treated with Estradiol] results in decreased expression of ATRNL1 mRNA26496021
C006780bisphenol Abisphenol A affects the expression of ATRNL1 mRNA21786754
C006780bisphenol A[bisphenol A co-treated with Estradiol] results in decreased expression of ATRNL1 mRNA26496021
C006780bisphenol Abisphenol A results in increased expression of ATRNL1 mRNA29097150
D001895BoronBoron results in increased expression of ATRNL1 mRNA21625915
D002251Carbon TetrachlorideCarbon Tetrachloride results in decreased expression of ATRNL1 mRNA17484886
D002794Choline[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of ATRNL1 mRNA20938992
C018021cobaltous chloridecobaltous chloride results in decreased expression of ATRNL1 mRNA24386269
D002945CisplatinCisplatin results in decreased expression of ATRNL1 mRNA25270620
D002945CisplatinCisplatin results in decreased expression of ATRNL1 mRNA22023808
D004041Dietary FatsDietary Fats results in increased expression of ATRNL1 mRNA19030233
D004041Dietary Fatsrimonabant inhibits the reaction [Dietary Fats results in increased expression of ATRNL1 mRNA]19030233
D004052Diethylnitrosamine[Diethylnitrosamine co-treated with Phenobarbital] results in decreased expression of ATRNL1 mRNA24535843
D004052DiethylnitrosamineDiethylnitrosamine results in decreased expression of ATRNL1 mRNA24535843
D004052Diethylnitrosamine[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of ATRNL1 mRNA22129741
D004997Ethinyl EstradiolEthinyl Estradiol results in increased expression of ATRNL1 mRNA29097150
D005492Folic Acid[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of ATRNL1 mRNA20938992
D004397FonofosFonofos results in increased methylation of ATRNL1 promoter22847954
D005947Glucose[INS protein co-treated with Glucose] results in decreased expression of ATRNL1 mRNA22634610
C016517indole-3-carbinolindole-3-carbinol affects the expression of ATRNL1 mRNA21396975
C016517indole-3-carbinol[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of ATRNL1 mRNA22129741
D008627Mercuric ChlorideMercuric Chloride affects the expression of ATRNL1 mRNA20353558
D008715Methionine[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of ATRNL1 mRNA20938992
D016685MitomycinMitomycin results in decreased expression of ATRNL1 mRNA25270620
C016599mono-(2-ethylhexyl)phthalatemono-(2-ethylhexyl)phthalate results in increased expression of ATRNL1 mRNA22401849
D009966OrphenadrineOrphenadrine affects the expression of ATRNL1 mRNA23665939
C030110oxaliplatin[oxaliplatin co-treated with Topotecan] results in decreased expression of ATRNL1 mRNA25729387
D010278ParathionParathion results in increased methylation of ATRNL1 promoter22847954
D010634Phenobarbital[Diethylnitrosamine co-treated with Phenobarbital] results in decreased expression of ATRNL1 mRNA24535843
D010634PhenobarbitalNR1I3 protein affects the reaction [Phenobarbital results in decreased expression of ATRNL1 mRNA]19482888
D010634PhenobarbitalPhenobarbital results in decreased expression of ATRNL1 mRNA19482888
D011441PropylthiouracilPropylthiouracil results in decreased expression of ATRNL1 mRNA24780913
C089032rimonabantrimonabant inhibits the reaction [Dietary Fats results in increased expression of ATRNL1 mRNA]19030233
D012969Sodium FluorideSodium Fluoride results in decreased expression of ATRNL1 mRNA27862939
C012568terbufosterbufos results in increased methylation of ATRNL1 promoter22847954
D013749Tetrachlorodibenzodioxin[Estradiol co-treated with Tetrachlorodibenzodioxin] results in decreased expression of ATRNL1 mRNA19619570
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in decreased expression of ATRNL1 mRNA19619570
C009495titanium dioxidetitanium dioxide results in decreased expression of ATRNL1 mRNA23557971
D019772Topotecan[oxaliplatin co-treated with Topotecan] results in decreased expression of ATRNL1 mRNA25729387
D014212TretinoinTretinoin results in increased expression of ATRNL1 mRNA21934132
C012589trichostatin Atrichostatin A results in increased expression of ATRNL1 mRNA24935251|2854253
D014403TubocurarineTubocurarine results in decreased expression of ATRNL1 mRNA19728367
D014635Valproic Acid"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ATRNL1 mRNA"27188386
D014635Valproic AcidValproic Acid affects the expression of ATRNL1 mRNA25979313
D014635Valproic AcidValproic Acid results in decreased methylation of ATRNL1 gene29154799
D014635Valproic AcidValproic Acid results in increased expression of ATRNL1 mRNA23179753|2438349
D001335Vehicle EmissionsVehicle Emissions results in increased methylation of ATRNL1 gene25560391
C029297vinylidene chloridevinylidene chloride results in decreased expression of ATRNL1 mRNA26682919

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0030246carbohydrate binding-IEA-  
GO ID GO Term Qualifier Evidence PubMed
GO:0007186G-protein coupled receptor signaling pathway-IEA-  
GO ID GO Term Qualifier Evidence PubMed
GO:0016021integral component of membrane-IEA-  
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal