Gene: OR51B5

282763
HOR5'Beta5|OR11-37
olfactory receptor family 51 subfamily B member 5
protein-coding
11p15.4
Ensembl:ENSG00000167355 Vega:OTTHUMG00000066676 UniprotKB:Q9H339
NC_000011.10
SNP Mapped
1   ANCO-SNPs
ND
0   
NA (AD)  NA (ND)   (Frontal_Cortex)
4.872e-1 (AD)  2.131e-1 (ND)

ANCO-SNPs

SNP ID Position Alleles Trait Variation Type
rs366533chr11:5496255 (GRCh38.p7)G>Anicotine dependenceSNV(Single Nucleotide Variation)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
SULT1C30.628
OR5AP20.625
OR5H10.617
SLCO1B30.613
OR9K20.602
OR8D20.602
OR2G30.602
OR4M20.595
OR5AN10.594
OR1L40.588

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
SPDEF-0.262
CDT1-0.251
C16orf95-0.244
FGF22-0.228
HAGHL-0.226
GALR3-0.225
C9orf24-0.222
CYP2D6-0.219
HES6-0.219
SLC25A10-0.218

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
C058305phenethyl isothiocyanatephenethyl isothiocyanate results in decreased expression of OR51B5 mRNA26678675

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0004930G-protein coupled receptor activity-IEA-  
GO:0004984olfactory receptor activity-IBA21873635  
GO:0004984olfactory receptor activity-NAS11121057  
GO ID GO Term Qualifier Evidence PubMed
GO:0007165signal transduction-IBA21873635  
GO:0007186G-protein coupled receptor signaling pathway-IEA-  
GO:0007608sensory perception of smell-NAS11121057  
GO:0050911detection of chemical stimulus involved in sensory perception of smell-IEA-  
GO ID GO Term Qualifier Evidence PubMed
GO:0005886plasma membrane-IBA21873635  
GO:0005886plasma membrane-TAS-  
GO:0016021integral component of membrane-NAS11121057  
KEGG ID KEGG Term
hsa04740Olfactory transduction
Reactome ID Reactome Term Evidence
R-HSA-162582Signal TransductionTAS
R-HSA-372790Signaling by GPCRTAS
R-HSA-381753Olfactory Signaling PathwayTAS
R-HSA-388396GPCR downstream signallingTAS
R-HSA-418555G alpha (s) signalling eventsTAS

Interactions (STRING v10.5, Interaction Score >= 0.400)

There is no Interaction data for this gene.

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal