Gene: TMEM150B

284417
DRAM3|TMEM224|TTN2
transmembrane protein 150B
protein-coding
19q13.42
Ensembl:ENSG00000180061 MIM:617291 Vega:OTTHUMG00000180709 UniprotKB:A6NC51
NC_000019.10
SNP Mapped
1   ANCO-SNPs
AD
0   
NA (AD)  NA (ND)   (Frontal_Cortex)
5.008e-1 (AD)  5.738e-1 (ND)

ANCO-SNPs

SNP ID Position Alleles Trait Variation Type
rs11084394chr19:55330677 (GRCh38.p7)T>Calcohol dependenceSNV(Single Nucleotide Variation)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
LRRC250.755
SIGLEC70.747
CD1800.745
FERMT30.728
TRIM50.728
GBP30.724
NLRC50.724
NMI0.724
DTX3L0.722
GBP10.718

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
C12orf54-0.424
SLC7A4-0.42
BFSP1-0.414
TPBGL-0.409
ZSCAN1-0.406
PPEF1-0.402
CHRNB2-0.396
ROBO2-0.393
GAD2-0.393
MARCH4-0.392

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
C006780bisphenol Abisphenol A results in increased methylation of TMEM150B gene28505145
D004041Dietary FatsDietary Fats results in increased expression of TMEM150B mRNA25016146
D019422Dietary SucroseDietary Sucrose results in increased expression of TMEM150B mRNA26033743
C039281furanfuran results in increased methylation of TMEM150B gene22079235
C561695(+)-JQ1 compound(+)-JQ1 compound results in decreased expression of TMEM150B mRNA26752646
C045463leflunomideleflunomide results in increased expression of TMEM150B mRNA28988120
D011192Potassium DichromatePotassium Dichromate results in increased expression of TMEM150B mRNA23608068
C045362prochlorazprochloraz results in increased expression of TMEM150B mRNA21470553
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the expression of TMEM150B mRNA26377647

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO ID GO Term Qualifier Evidence PubMed
GO:0006914autophagy-IEA-  
GO:0010506regulation of autophagy-IBA21873635  
GO ID GO Term Qualifier Evidence PubMed
GO:0000421autophagosome membrane-IEA-  
GO:0005764lysosome-IBA21873635  
GO:0005887integral component of plasma membrane-IDA25608530  
GO:0010008endosome membrane-IEA-  
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal