Gene: MALRD1

340895
C10orf112|DIET1|bA265G8.2
MAM and LDL receptor class A domain containing 1
protein-coding
10p12.31
Ensembl:ENSG00000204740 MIM:617715 Vega:OTTHUMG00000017779 UniprotKB:Q5VYJ5
NC_000010.11
SNP Mapped
3   ANCO-SNPs
AD
0   
NA (AD)  NA (ND)   (Frontal_Cortex)
NA (AD)  NA (ND)

ANCO-SNPs

SNP ID Position Alleles Trait Variation Type
rs10494868chr10:19518946 (GRCh38.p7)C>Aalcohol dependenceSNV(Single Nucleotide Variation)
rs3852465chr10:19507501 (GRCh38.p7)T>Calcohol dependenceSNV(Single Nucleotide Variation)
rs6481955chr10:19506116 (GRCh38.p7)A>Galcohol dependenceSNV(Single Nucleotide Variation)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
D018501Antirheumatic AgentsAntirheumatic Agents results in increased expression of MALRD1 mRNA24449571
C006780bisphenol Abisphenol A results in decreased expression of MALRD1 mRNA25181051
C006780bisphenol Abisphenol A results in increased methylation of MALRD1 gene28505145
C045463leflunomideleflunomide results in increased expression of MALRD1 mRNA28988120
D008741Methyl MethanesulfonateMethyl Methanesulfonate results in decreased expression of MALRD1 mRNA26011545

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO ID GO Term Qualifier Evidence PubMed
GO:0042632cholesterol homeostasis-IEA-  
GO:0070858negative regulation of bile acid biosynthetic process-IEA-  
GO ID GO Term Qualifier Evidence PubMed
GO:0005794Golgi apparatus-IDA-  
GO:0016021integral component of membrane-IEA-  
GO:0030659cytoplasmic vesicle membrane-IEA-  
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal