Gene: IGFBP7

3490
AGM|FSTL2|IBP-7|IGFBP-7|IGFBP-7v|IGFBPRP1|MAC25|PSF|RAMSVPS|TAF
insulin like growth factor binding protein 7
protein-coding
4q12
Ensembl:ENSG00000163453 MIM:602867 Vega:OTTHUMG00000128772 UniprotKB:Q16270
NG_031877.1
PubMed|SNP Mapped
1   ANCO-SNPs
CD|OD|ND|AD
3   
1.899e-1 (AD)  4.261e-1 (ND)   (Frontal_Cortex)
1.638e-1 (AD)  8.574e-2 (ND)

ANCO-SNPs

SNP ID Position Alleles Trait Variation Type
rs35769988chr4:57050723-57050738 (GRCh38.p7)delTalcohol dependenceIndel(Insertion and Deletion)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
MSN0.848
FCGRT0.847
PTTG1IP0.846
VIM0.844
STOM0.84
EPS80.836
RHOC0.83
ANXA50.83
HLA-A0.826
IFITM30.825

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
ABCC12-0.508
SLC7A4-0.505
PPEF1-0.504
KCNB2-0.495
OR4F29-0.49
CALHM1-0.481
MARCH4-0.472
GABRG3-0.471
OR4F5-0.467
GPR61-0.466

Drugs/Compounds

ID Drug Name Drug Type CAS Num Status Role
DB00030Insulin HumanBiotechDrug11061-68-0Approved|InvestigationalTarget
DB00071Insulin PorkBiotechDrug12584-58-6ApprovedTarget
ID Drug Name Action PubMed
C0230353,4,5,3',4'-pentachlorobiphenyl"3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of IGFBP7 mRNA"23196670
C4727913-(4'-hydroxy-3'-adamantylbiphenyl-4-yl)acrylic acid3-(4'-hydroxy-3'-adamantylbiphenyl-4-yl)acrylic acid results in increased expression of IGFBP7 mRNA16788091
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with entinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of IGFBP7 mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with mercuric bromide co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of IGFBP7 mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with panobinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of IGFBP7 mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of IGFBP7 mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with trichostatin A co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of IGFBP7 mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of IGFBP7 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with entinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of IGFBP7 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with mercuric bromide co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of IGFBP7 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with panobinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of IGFBP7 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of IGFBP7 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with trichostatin A co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of IGFBP7 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of IGFBP7 mRNA"27188386
D000082AcetaminophenAcetaminophen results in increased expression of IGFBP7 mRNA29067470
D000082AcetaminophenAcetaminophen affects the expression of IGFBP7 mRNA17562736
D020106AcrylamideAcrylamide results in decreased expression of IGFBP7 mRNA28959563
D016604Aflatoxin B1Aflatoxin B1 affects the expression of IGFBP7 protein20106945
D016604Aflatoxin B1Aflatoxin B1 results in increased expression of IGFBP7 mRNA21632981|2164198
D016604Aflatoxin B1Aflatoxin B1 results in increased expression of IGFBP7 mRNA19770486
D016718Arachidonic AcidArachidonic Acid results in decreased expression of IGFBP7 mRNA16704987
C006632arsenic trioxidearsenic trioxide results in decreased expression of IGFBP7 mRNA15725085
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased expression of IGFBP7 mRNA20106945|2163298
D001564Benzo(a)pyreneAHR protein promotes the reaction [Benzo(a)pyrene results in decreased expression of IGFBP7 mRNA]15034205
D001564Benzo(a)pyreneBenzo(a)pyrene results in decreased expression of IGFBP7 mRNA15034205
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased expression of IGFBP7 mRNA22228805
C095105bexarotene[bexarotene co-treated with Tamoxifen] results in decreased expression of IGFBP7 mRNA17630414
C006780bisphenol Abisphenol A results in decreased expression of IGFBP7 mRNA25181051
C006780bisphenol Abisphenol A results in increased methylation of IGFBP7 gene28505145
C005961bis(tri-n-butyltin)oxidebis(tri-n-butyltin)oxide results in increased expression of IGFBP7 mRNA18958704
D002065BuspironeBuspirone results in decreased expression of IGFBP7 mRNA24136188
C027561butylbenzyl phthalatebutylbenzyl phthalate results in decreased expression of IGFBP7 mRNA19560483
D002104CadmiumCadmium results in decreased expression of IGFBP7 mRNA24084258
D019256Cadmium Chloride[sodium arsenite co-treated with Cadmium Chloride co-treated with chromic oxide co-treated with chromous chloride co-treated with lead acetate] results in decreased expression of IGFBP7 mRNA12634122
D002220CarbamazepineCarbamazepine affects the expression of IGFBP7 mRNA25979313
D002251Carbon TetrachlorideCarbon Tetrachloride results in increased expression of IGFBP7 mRNA27339419
D002251Carbon TetrachlorideCarbon Tetrachloride results in increased expression of IGFBP7 mRNA16239168
C100187chloropicrinchloropicrin results in decreased expression of IGFBP7 mRNA26352163|2847649
C023600chromic oxide[sodium arsenite co-treated with Cadmium Chloride co-treated with chromic oxide co-treated with chromous chloride co-treated with lead acetate] results in decreased expression of IGFBP7 mRNA12634122
C017133chromous chloride[sodium arsenite co-treated with Cadmium Chloride co-treated with chromic oxide co-treated with chromous chloride co-treated with lead acetate] results in decreased expression of IGFBP7 mRNA12634122
D060729Coal AshCoal Ash results in increased expression of IGFBP7 mRNA19000753
C018021cobaltous chloridecobaltous chloride results in decreased expression of IGFBP7 mRNA19320972
C018021cobaltous chloridecobaltous chloride results in decreased secretion of IGFBP7 protein22079246
D003300Copper[Disulfiram binds to Copper] which results in increased expression of IGFBP7 mRNA24690739
D003300Copper[Disulfiram binds to Copper] which results in increased expression of IGFBP7 protein24690739
D003471CuprizoneCuprizone results in increased expression of IGFBP7 mRNA27523638
D003474CurcuminCurcumin results in increased expression of IGFBP7 mRNA21594647
D016572CyclosporineCyclosporine results in decreased expression of IGFBP7 mRNA25562108|2798913
D016572CyclosporineCyclosporine results in increased expression of IGFBP7 mRNA20106945|2163298
D000069439DasatinibDasatinib results in increased expression of IGFBP7 mRNA20579391
C010902decabromobiphenyl etherdecabromobiphenyl ether affects the expression of IGFBP7 mRNA24834073
C014347decitabinedecitabine affects the methylation of IGFBP7 exon17334979
C014347decitabinedecitabine inhibits the reaction [Smoke results in decreased expression of IGFBP7 mRNA]21095227
C014347decitabinedecitabine results in increased expression of IGFBP7 mRNA16367923|1898172
C014347decitabinedecitabine results in increased expression of IGFBP7 protein18981723
D013759DronabinolDronabinol results in increased expression of IGFBP7 mRNA18163980
C088674dibromoacetic aciddibromoacetic acid results in decreased expression of IGFBP7 mRNA21046364
D003993Dibutyl PhthalateDibutyl Phthalate results in decreased expression of IGFBP7 mRNA19560483
D002945CisplatinCisplatin affects the expression of IGFBP7 mRNA21151649
D004041Dietary FatsDietary Fats results in increased expression of IGFBP7 mRNA18457598|1850357
D004051Diethylhexyl PhthalateDiethylhexyl Phthalate results in decreased expression of IGFBP7 mRNA19560483
D004052DiethylnitrosamineDiethylnitrosamine results in increased expression of IGFBP7 mRNA19638242
C034171di-n-pentyl phthalatedi-n-pentyl phthalate results in decreased expression of IGFBP7 mRNA19560483
D004221Disulfiram[Disulfiram binds to Copper] which results in increased expression of IGFBP7 mRNA24690739
D004221Disulfiram[Disulfiram binds to Copper] which results in increased expression of IGFBP7 protein24690739
D004317DoxorubicinIGFBP7 protein affects the susceptibility to Doxorubicin16217747
C118739entinostatentinostat results in increased expression of IGFBP7 mRNA26272509
C118739entinostat"[NOG protein co-treated with entinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of IGFBP7 mRNA"27188386
D004997Ethinyl EstradiolEthinyl Estradiol results in increased expression of IGFBP7 mRNA17108234
D005047EtoposideIGFBP7 protein affects the susceptibility to Etoposide16217747
C039281furanfuran results in increased expression of IGFBP7 mRNA27387713
D017313FenretinideFenretinide results in increased expression of IGFBP7 mRNA28973697
C561695(+)-JQ1 compound(+)-JQ1 compound results in decreased expression of IGFBP7 mRNA24796395
C008261lead acetate[sodium arsenite co-treated with Cadmium Chloride co-treated with chromic oxide co-treated with chromous chloride co-treated with lead acetate] results in decreased expression of IGFBP7 mRNA12634122
C482199lipopolysaccharide, E coli O55-B5"lipopolysaccharide, E coli O55-B5 results in decreased expression of IGFBP7 mRNA"24972896
C042720mercuric bromidemercuric bromide results in increased expression of IGFBP7 mRNA26272509
C042720mercuric bromide"[NOG protein co-treated with mercuric bromide co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of IGFBP7 mRNA"27188386
D008727MethotrexateIGFBP7 protein affects the susceptibility to Methotrexate16217747
C004925methylmercuric chloridemethylmercuric chloride results in decreased expression of IGFBP7 mRNA28001369
D008777MethyltestosteroneMethyltestosterone results in increased expression of IGFBP7 mRNA29191790
D008942MitoxantroneIGFBP7 protein affects the susceptibility to Mitoxantrone16217747
C523799MRK 003MRK 003 results in decreased expression of IGFBP7 mRNA21169257
C523799MRK 003IGFBP7 results in decreased susceptibility to MRK 00319903844
D0150581-Naphthylisothiocyanate1-Naphthylisothiocyanate results in increased expression of IGFBP7 mRNA25380136
C051752nefazodonenefazodone results in decreased expression of IGFBP7 mRNA24136188
D009532NickelNickel results in decreased expression of IGFBP7 mRNA24084258
C012655nimesulidenimesulide results in decreased expression of IGFBP7 mRNA24136188
C030110oxaliplatin[oxaliplatin co-treated with Topotecan] results in increased expression of IGFBP7 mRNA25729387
C030110oxaliplatinoxaliplatin results in increased expression of IGFBP7 mRNA25729387
D010126OzoneOzone results in decreased expression of IGFBP7 mRNA12763052
C496932panobinostat"[NOG protein co-treated with panobinostat co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of IGFBP7 mRNA"27188386
C496932panobinostatpanobinostat results in increased expression of IGFBP7 mRNA26272509
C027579periodate-oxidized adenosineperiodate-oxidized adenosine affects the expression of IGFBP7 mRNA17097637
D010662Phenylmercuric Acetate"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of IGFBP7 mRNA"27188386
D010662Phenylmercuric AcetatePhenylmercuric Acetate results in increased expression of IGFBP7 mRNA26272509
D010705PhosgenePhosgene affects the expression of IGFBP7 mRNA16300373
C027373potassium chromate(VI)potassium chromate(VI) results in decreased expression of IGFBP7 mRNA22714537
D011441PropylthiouracilPropylthiouracil results in decreased expression of IGFBP7 mRNA24780913
C513428pyrachlostrobinpyrachlostrobin results in increased expression of IGFBP7 mRNA27029645
D011794QuercetinQuercetin results in increased expression of IGFBP7 mRNA16455785
C010327salinomycinsalinomycin results in decreased expression of IGFBP7 mRNA19682730
D012715Sesame OilSesame Oil results in decreased expression of IGFBP7 mRNA29191790
D012834SilverSilver results in decreased expression of IGFBP7 mRNA27131904
D012906Smokedecitabine inhibits the reaction [Smoke results in decreased expression of IGFBP7 mRNA]21095227
C017947sodium arsenite[sodium arsenite co-treated with Cadmium Chloride co-treated with chromic oxide co-treated with chromous chloride co-treated with lead acetate] results in decreased expression of IGFBP7 mRNA12634122
D018038Sodium SeleniteSodium Selenite results in increased expression of IGFBP7 mRNA18175754
D012999SomanSoman results in increased expression of IGFBP7 mRNA19281266
D013629TamoxifenTamoxifen results in increased expression of IGFBP7 mRNA25123088
D013629Tamoxifen[bexarotene co-treated with Tamoxifen] results in decreased expression of IGFBP7 mRNA17630414
D013739TestosteroneTestosterone results in decreased expression of IGFBP7 mRNA20403060
D013739TestosteroneTestosterone results in increased expression of IGFBP7 mRNA20403060
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in decreased expression of IGFBP7 mRNA17101203|2010694
D013749TetrachlorodibenzodioxinAHR protein promotes the reaction [Tetrachlorodibenzodioxin results in decreased expression of IGFBP7 mRNA]15034205
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in decreased expression of IGFBP7 mRNA15034205
D013755Tetradecanoylphorbol Acetate[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of IGFBP7 mRNA16979875
D019772TopotecanIGFBP7 protein affects the susceptibility to Topotecan16217747
D019772Topotecan[oxaliplatin co-treated with Topotecan] results in increased expression of IGFBP7 mRNA25729387
D019772TopotecanTopotecan results in increased expression of IGFBP7 mRNA25729387
D014212TretinoinTretinoin results in decreased expression of IGFBP7 mRNA23724009
D014212TretinoinTretinoin results in increased expression of IGFBP7 mRNA21934132
C034613triacsin Ctriacsin C results in decreased expression of IGFBP7 mRNA16704987
C011559tributyltintributyltin results in increased expression of IGFBP7 mRNA29191790
C012589trichostatin A"[NOG protein co-treated with trichostatin A co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of IGFBP7 mRNA"27188386
C012589trichostatin Atrichostatin A results in increased expression of IGFBP7 mRNA24935251|2627250
C016805tris(1,3-dichloro-2-propyl)phosphate"tris(1,3-dichloro-2-propyl)phosphate results in decreased expression of IGFBP7 mRNA"26179874
D014520UrethaneUrethane results in decreased expression of IGFBP7 mRNA28818685
D014635Valproic Acid"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of IGFBP7 mRNA"27188386
D014635Valproic AcidValproic Acid results in decreased expression of IGFBP7 mRNA29154799
D014635Valproic AcidValproic Acid results in increased expression of IGFBP7 mRNA23179753|2438349
D014635Valproic AcidValproic Acid affects the expression of IGFBP7 mRNA17963808
D014638VanadatesVanadates results in increased expression of IGFBP7 mRNA22714537
D001335Vehicle EmissionsVehicle Emissions results in decreased expression of IGFBP7 mRNA19165385
C025643vinclozolinvinclozolin affects the expression of IGFBP7 mRNA19015723
D015032ZincZinc affects the expression of IGFBP7 mRNA16979875
D015032Zinc[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of IGFBP7 mRNA16979875

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0005515protein binding-IPI9388210  
GO:0005520insulin-like growth factor binding-IEA-  
GO ID GO Term Qualifier Evidence PubMed
GO:0001558regulation of cell growth-IEA-  
GO:0007155cell adhesion-IDA8117260  
GO:0007566embryo implantation-IEA-  
GO:0008285negative regulation of cell proliferation-TAS8939990  
GO:0009408response to heat-IEA-  
GO:0032526response to retinoic acid-IEA-  
GO:0032870cellular response to hormone stimulus-IEA-  
GO:0043687post-translational protein modification-TAS-  
GO:0044267cellular protein metabolic process-TAS-  
GO:0050810regulation of steroid biosynthetic process-IEA-  
GO:0051414response to cortisol-IEA-  
GO ID GO Term Qualifier Evidence PubMed
GO:0005576extracellular region-HDA27068509  
GO:0005576extracellular region-TAS-  
GO:0005615extracellular space-HDA20551380  
GO:0005788endoplasmic reticulum lumen-TAS-  
GO:0062023collagen-containing extracellular matrix-HDA27559042  
GO:0062023collagen-containing extracellular matrixcolocalizes_withHDA20551380  
GO:0070062extracellular exosome-HDA23533145  
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence
R-HSA-2262752Cellular responses to stressTAS
R-HSA-2559582Senescence-Associated Secretory Phenotype (SASP)TAS
R-HSA-2559583Cellular SenescenceTAS
R-HSA-381426Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)TAS
R-HSA-392499Metabolism of proteinsTAS
R-HSA-597592Post-translational protein modificationTAS
R-HSA-8953897Cellular responses to external stimuliTAS
R-HSA-8957275Post-translational protein phosphorylationTAS

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
24690739Disulfiram suppresses growth of the malignant pleural mesothelioma cells in part by inducing apoptosis. (2014)Cheriyan VTPLoS One
21945224Biomarkers of the insulin-like growth factor pathway predict progression and outcome in lung cancer. (2011 Nov)Shersher DDAnn Thorac Surg
27762075Sex-specific linkage scans in opioid dependence. (2017 Apr)Yang BZAm J Med Genet B Neuropsychiatr Genet