Gene: MROH7

374977
C1orf175|HEATR8
maestro heat like repeat family member 7
protein-coding
1p32.3
Ensembl:ENSG00000184313 Vega:OTTHUMG00000009890 UniprotKB:Q68CQ1
NC_000001.11
SNP Mapped
1   ANCO-SNPs
ND|AD
0   
4.441e-1 (AD)  6.630e-1 (ND)   (Frontal_Cortex)
NA (AD)  NA (ND)

ANCO-SNPs

SNP ID Position Alleles Trait Variation Type
rs1368882chr1:54641346 (GRCh38.p7)G>Aalcohol dependence|nicotine dependenceSNV(Single Nucleotide Variation)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
ANO80.785
ANKDD1A0.78
TPCN10.779
NINL0.772
TRIM450.767
ADAMTS170.76
SPPL2B0.759
RYR10.759
PLEC0.755
NAV20.753

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
OR4F5-0.341
C17orf112-0.338
TMSB15A-0.335
HAS2-0.332
WDR72-0.325
C19orf33-0.317
KRTAP1-1-0.311
SGMS2-0.31
DLEU1-0.308
CLEC6A-0.307

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
C0297902,2',3',4,4',5-hexachlorobiphenyl"[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in decreased expression of MROH7 mRNA"25510870
C0817662,4,4'-trichlorobiphenyl"[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in decreased expression of MROH7 mRNA"25510870
C0140242,4,5,2',4',5'-hexachlorobiphenyl"[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in decreased expression of MROH7 mRNA"25510870
C0098282,4,5,2',5'-pentachlorobiphenyl"[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in decreased expression of MROH7 mRNA"25510870
C0094072,5,2',5'-tetrachlorobiphenyl"[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in decreased expression of MROH7 mRNA"25510870
D016604Aflatoxin B1Aflatoxin B1 results in decreased methylation of MROH7 gene27153756
C006780bisphenol Abisphenol A affects the expression of MROH7 mRNA25181051
D003471CuprizoneCuprizone results in increased expression of MROH7 mRNA26577399
D004397FonofosFonofos results in increased methylation of MROH7 promoter22847954
C561695(+)-JQ1 compound(+)-JQ1 compound results in increased expression of MROH7 mRNA26752646
D010100OxygenOxygen deficiency results in increased expression of MROH7 mRNA26516004
D010278ParathionParathion results in increased methylation of MROH7 promoter22847954
C410127PCB 180"[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with PCB 180] results in decreased expression of MROH7 mRNA"25510870
D010936Plant ExtractsPlant Extracts results in decreased expression of MROH7 mRNA23557933
D011441PropylthiouracilPropylthiouracil results in decreased expression of MROH7 mRNA24780913
D012822Silicon DioxideSilicon Dioxide analog results in decreased expression of MROH7 mRNA25895662
C012568terbufosterbufos results in increased methylation of MROH7 promoter22847954

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO ID GO Term Qualifier Evidence PubMed
GO ID GO Term Qualifier Evidence PubMed
GO:0005615extracellular space-HDA22664934  
GO:0016021integral component of membrane-IEA-  
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence

Interactions (STRING v10.5, Interaction Score >= 0.400)

There is no Interaction data for this gene.

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal