Gene: CASC15

401237
CANT|LINC00340|lnc-SOX4-1
cancer susceptibility 15
ncRNA
6p22.3
Ensembl:ENSG00000272168 MIM:616610
NC_000006.12
SNP Mapped
3   ANCO-SNPs
AD
0   
6.967e-1 (AD)  6.308e-1 (ND)   (Frontal_Cortex)
3.415e-2 (AD)  9.315e-1 (ND)

ANCO-SNPs

SNP ID Position Alleles Trait Variation Type
rs726730chr6:21995879 (GRCh38.p7)A>Galcohol dependenceSNV(Single Nucleotide Variation)
rs9350404chr6:21994515 (GRCh38.p7)A>Galcohol dependenceSNV(Single Nucleotide Variation)
rs2479808chr6:21824163 (GRCh38.p7)C>Talcohol dependenceSNV(Single Nucleotide Variation)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
XKR40.88
TMEM1690.859
MAGI10.855
FBXO90.854
PTPRR0.848
SLC39A100.843
SLC8A30.842
NALCN0.841
NREP0.84
LRRTM30.838

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
TGIF1-0.598
RAB13-0.575
EMP3-0.573
HEBP2-0.57
TEAD3-0.57
FXYD3-0.561
PXDC1-0.554
ATOH8-0.554
A4GALT-0.553
GPR4-0.553

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
D004958EstradiolEstradiol results in decreased expression of CASC15 mRNA25321415
C543008bis(4-hydroxyphenyl)sulfone[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bis(4-hydroxyphenyl)sulfone] results in increased expression of CASC15 mRNA28628672
C018475butyraldehydebutyraldehyde results in increased expression of CASC15 mRNA26079696
D002392Catechin[Catechin co-treated with Grape Seed Proanthocyanidins] results in increased expression of CASC15 mRNA24763279
D016572CyclosporineCyclosporine results in decreased expression of CASC15 mRNA27989131
D003907DexamethasoneDexamethasone results in decreased expression of CASC15 mRNA25047013
D003907Dexamethasone[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bis(4-hydroxyphenyl)sulfone] results in increased expression of CASC15 mRNA28628672
D002945Cisplatin[Cisplatin co-treated with jinfukang] results in decreased expression of CASC15 mRNA27392435
D002945CisplatinCisplatin results in decreased expression of CASC15 mRNA27392435
C511402Grape Seed Proanthocyanidins[Catechin co-treated with Grape Seed Proanthocyanidins] results in increased expression of CASC15 mRNA24763279
D007213Indomethacin[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bis(4-hydroxyphenyl)sulfone] results in increased expression of CASC15 mRNA28628672
D0150561-Methyl-3-isobutylxanthine[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bis(4-hydroxyphenyl)sulfone] results in increased expression of CASC15 mRNA28628672
C544151jinfukang[Cisplatin co-treated with jinfukang] results in decreased expression of CASC15 mRNA27392435
D009532NickelNickel results in decreased expression of CASC15 mRNA24768652|2558310
C005556propionaldehydepropionaldehyde results in increased expression of CASC15 mRNA26079696
D012822Silicon DioxideSilicon Dioxide analog results in decreased expression of CASC15 mRNA25895662
D014028Tobacco Smoke PollutionTobacco Smoke Pollution results in increased expression of CASC15 mRNA28065790
D014635Valproic AcidValproic Acid results in decreased expression of CASC15 mRNA29154799

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO ID GO Term Qualifier Evidence PubMed
GO ID GO Term Qualifier Evidence PubMed
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence

Interactions (STRING v10.5, Interaction Score >= 0.400)

There is no Interaction data for this gene.

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal