Gene: LINC00158

54072
C21orf42|NCRNA00158
long intergenic non-protein coding RNA 158
ncRNA
21q21.2
Ensembl:ENSG00000185433 UniprotKB:P58513
NC_000021.9
SNP Mapped
4   ANCO-SNPs
ND
0   
NA (AD)  NA (ND)   (Frontal_Cortex)
4.634e-3 (AD)  1.377e-1 (ND)

ANCO-SNPs

SNP ID Position Alleles Trait Variation Type
rs547301762chr21:25413996-25413999 (GRCh38.p7)dupTGCTnicotine dependenceIndel(Insertion and Deletion)
rs2829746chr21:25425777 (GRCh38.p7)G>Anicotine dependenceSNV(Single Nucleotide Variation)
rs2829735chr21:25413995 (GRCh38.p7)C>Anicotine dependenceSNV(Single Nucleotide Variation)
rs2829729chr21:25397616 (GRCh38.p7)T>Cnicotine dependenceSNV(Single Nucleotide Variation)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
NPHP10.668
AMY2B0.663
TRAIP0.658
MAATS10.655
GEN10.651
AKR7L0.641
DPY19L20.641
ATP6V0A20.636
TTC21A0.63
FAM153C0.627

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
PGF-0.307
CD8B-0.285
GZMA-0.28
LYL1-0.269
RUNX3-0.265
TFPI2-0.263
CCND1-0.261
TMSB15A-0.255
KLRC2-0.255
ZNF114-0.254

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
D016604Aflatoxin B1Aflatoxin B1 results in decreased methylation of LINC00158 gene27153756
D014635Valproic AcidValproic Acid results in decreased methylation of LINC00158 gene29154799

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO ID GO Term Qualifier Evidence PubMed
GO ID GO Term Qualifier Evidence PubMed
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence

Interactions (STRING v10.5, Interaction Score >= 0.400)

There is no Interaction data for this gene.

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal