Gene: ARMC4

55130
CILD23
armadillo repeat containing 4
protein-coding
10p12.1
Ensembl:ENSG00000169126 MIM:615408 Vega:OTTHUMG00000017867 UniprotKB:Q5T2S8
NG_042820.1
PubMed|SNP Mapped
1   ANCO-SNPs
ND
1   
NA (AD)  NA (ND)   (Frontal_Cortex)
6.662e-1 (AD)  6.899e-1 (ND)

ANCO-SNPs

SNP ID Position Alleles Trait Variation Type
rs915175chr10:27844758 (GRCh38.p7)C>Tnicotine dependenceSNV(Single Nucleotide Variation)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
NUDT70.597
TMEM2090.589
PNPLA40.579
LYPLAL10.571
GSTCD0.571
TCTN10.57
CNTNAP30.566
TMEM2310.564
SRR0.56
ZNF7300.559

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
PTGDR2-0.3
C14orf180-0.259
EPPIN-0.256
LBX2-0.256
ETV4-0.255
RNF223-0.244
TTLL10-0.241
TAS2R13-0.241
OR2L8-0.24
HS3ST6-0.24

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of ARMC4 mRNA"27188386
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of ARMC4 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of ARMC4 mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of ARMC4 mRNA"27188386
D000082AcetaminophenAcetaminophen results in increased expression of ARMC4 mRNA26690555
D000535Aluminum[APP protein modified form binds to Aluminum] which results in decreased expression of ARMC4 mRNA21298039
D001280AtrazineAtrazine results in decreased expression of ARMC4 mRNA25929836
C547126AZM551248AZM551248 results in decreased expression of ARMC4 mRNA22323515
C006780bisphenol Abisphenol A results in decreased expression of ARMC4 mRNA25181051
D003471CuprizoneCuprizone results in increased expression of ARMC4 mRNA26577399
C118739entinostatentinostat results in decreased expression of ARMC4 mRNA27188386
C045651epigallocatechin gallate[potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of ARMC4 mRNA22079256
C561695(+)-JQ1 compound(+)-JQ1 compound results in decreased expression of ARMC4 mRNA24796395|2675264
C011890kojic acidkojic acid results in increased expression of ARMC4 mRNA16595896
C004925methylmercuric chloridemethylmercuric chloride results in decreased expression of ARMC4 mRNA28001369
D037742Nanotubes, Carbon"Nanotubes, Carbon analog results in decreased expression of ARMC4 mRNA"25554681
D037742Nanotubes, Carbon"Nanotubes, Carbon results in decreased expression of ARMC4 mRNA"25554681
D010662Phenylmercuric Acetate"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of ARMC4 mRNA"27188386
C027373potassium chromate(VI)[potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of ARMC4 mRNA22079256
C027373potassium chromate(VI)potassium chromate(VI) results in decreased expression of ARMC4 mRNA22079256
D011441PropylthiouracilPropylthiouracil results in increased expression of ARMC4 mRNA24780913
D012969Sodium FluorideSodium Fluoride results in increased expression of ARMC4 protein28918527
D053260SootSoot results in decreased expression of ARMC4 mRNA26551751
D014028Tobacco Smoke PollutionTobacco Smoke Pollution results in decreased expression of ARMC4 mRNA28065790
D014212TretinoinTretinoin results in decreased expression of ARMC4 mRNA21934132
C012589trichostatin Atrichostatin A results in decreased expression of ARMC4 mRNA24935251
D014635Valproic Acid"[NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of ARMC4 mRNA"27188386
D014635Valproic AcidValproic Acid affects the expression of ARMC4 mRNA25979313
D014635Valproic AcidValproic Acid results in decreased expression of ARMC4 mRNA23179753|2438349
D014638VanadatesVanadates results in decreased expression of ARMC4 mRNA22714537

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO ID GO Term Qualifier Evidence PubMed
GO:0003341cilium movement-IMP23849778  24203976  
GO:0003356regulation of cilium beat frequency-IMP24203976  
GO:0007368determination of left/right symmetry-IMP23849778  
GO:0007507heart development-IEA-  
GO:0021591ventricular system development-IEA-  
GO:0036158outer dynein arm assembly-IMP23849778  24203976  
GO ID GO Term Qualifier Evidence PubMed
GO:0005930axoneme-IDA23849778  24203976  
GO:0097546ciliary base-IDA23849778  
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
16809635Identification of novel lung genes in bronchial epithelium by serial analysis of gene expression. (2006 Dec)Lonergan KMAm J Respir Cell Mol Biol