Gene: CACNA1D

776
CACH3|CACN4|CACNL1A2|CCHL1A2|Cav1.3|PASNA|SANDD
calcium voltage-gated channel subunit alpha1 D
protein-coding
3p21.1
Ensembl:ENSG00000157388 MIM:114206 Vega:OTTHUMG00000158278 UniprotKB:Q01668
NG_032999.1
PubMed|SNP Mapped
1   ANCO-SNPs
CD|ND|AD
4   
NA (AD)  NA (ND)   (Frontal_Cortex)
2.677e-1 (AD)  3.332e-1 (ND)

ANCO-SNPs

SNP ID Position Alleles Trait Variation Type
rs6445588chr3:53596652 (GRCh38.p7)C>Tnicotine dependenceSNV(Single Nucleotide Variation)

DNA Methylation

Probe Locus(GRCh37) Gene Region p-val Trait PubMed ID
cg13411554chr3:53700276CACNA1D9.050e-8Maternal smoking in pregnancy27040690
cg13411554chr3:53700276CACNA1D3.830e-9Maternal smoking in pregnancy27040690
cg13411554chr3:53700276CACNA1D2.940e-8Maternal smoking in pregnancy27040690
cg00336149chr3:53700195CACNA1D1.300e-13Smoking27651444
cg15417641chr3:53700141CACNA1D6.900e-13Smoking27651444
cg21188533chr3:53700263CACNA1D2.900e-11Smoking27651444
cg13411554chr3:53700276CACNA1D2.400e-10Smoking27651444
cg21188533chr3:53700263CACNA1D1.240e-8Tobacco smoking28225026
cg00336149chr3:53700195CACNA1D4.310e-8Tobacco smoking28225026

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
CSMD10.955
CACNA1B0.947
UNC790.947
DLGAP20.939
DRP20.937
KIAA13240.936
RASAL20.93
LMTK20.928
GRIN2B0.926
SCN8A0.925

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
COPZ2-0.605
HEY2-0.597
RAB13-0.597
ROM1-0.584
MYL3-0.574
YES1-0.566
SNHG18-0.557
VAMP5-0.54
TSPO-0.538
HEBP2-0.525

Drugs/Compounds

ID Drug Name Drug Type CAS Num Status Role
DB11093Calcium CitrateSmall Molecule813-94-5ApprovedTransporter
DB11348Calcium PhosphateSmall Molecule10103-46-5ApprovedTransporter
DB00270IsradipineSmall Molecule75695-93-1Approved|InvestigationalTarget
DB00381AmlodipineSmall Molecule88150-42-9ApprovedTarget
DB00393NimodipineSmall Molecule66085-59-4Approved|InvestigationalTarget
DB00401NisoldipineSmall Molecule63675-72-9ApprovedTarget
DB00568CinnarizineSmall Molecule298-57-7Approved|InvestigationalTarget
DB00622NicardipineSmall Molecule55985-32-5Approved|InvestigationalTarget
DB00661VerapamilSmall Molecule52-53-9ApprovedTarget
DB00898EthanolSmall Molecule64-17-5ApprovedTarget
DB01023FelodipineSmall Molecule72509-76-3Approved|InvestigationalTarget
DB01054NitrendipineSmall Molecule39562-70-4Approved|InvestigationalTarget
DB01115NifedipineSmall Molecule21829-25-4ApprovedTarget
DB01388MibefradilSmall Molecule116644-53-2Investigational|WithdrawnTarget
DB04855DronedaroneSmall Molecule141626-36-0ApprovedTarget
DB04920ClevidipineSmall Molecule167221-71-8Approved|InvestigationalTarget
DB06712NilvadipineSmall Molecule75530-68-6Approved|InvestigationalTarget
DB09229AranidipineSmall Molecule86780-90-7Approved|InvestigationalTarget
DB00421SpironolactoneSmall Molecule52-01-7ApprovedTarget
DB09089TrimebutineSmall Molecule39133-31-8ApprovedTarget
DB09231BenidipineSmall Molecule105979-17-7Approved|InvestigationalTarget
DB09232CilnidipineSmall Molecule132203-70-4Approved|InvestigationalTarget
DB09236LacidipineSmall Molecule103890-78-4Approved|InvestigationalTarget
DB09238ManidipineSmall Molecule89226-50-6Approved|InvestigationalTarget
ID Drug Name Action PubMed
C0493251,2-dithiol-3-thione"1,2-dithiol-3-thione results in decreased expression of CACNA1D mRNA"19162173
C0369902-amino-3,8-dimethylimidazo(4,5-f)quinoxaline"2-amino-3,8-dimethylimidazo(4,5-f)quinoxaline results in decreased expression of CACNA1D mRNA"20816883
C5037722-aminomethyl-2-tricyclo(3.3.1.1(1,7))decaneacetic acid hydrochloride"2-aminomethyl-2-tricyclo(3.3.1.1(1,7))decaneacetic acid hydrochloride affects the activity of [CACNA1D protein co-treated with CACNB3 protein]"19796812
C5037722-aminomethyl-2-tricyclo(3.3.1.1(1,7))decaneacetic acid hydrochloride"CACNA2D1 protein results in increased susceptibility to [2-aminomethyl-2-tricyclo(3.3.1.1(1,7))decaneacetic acid hydrochloride affects the activity of [CACNA1D protein co-treated with CACNB3 protein]]"19796812
D000082Acetaminophen[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in increased expression of CACNA1D mRNA25607892
D000393Air PollutantsAir Pollutants analog results in decreased expression of CACNA1D mRNA21757418
D020875Enkephalin, Ala(2)-MePhe(4)-Gly(5)-"Enkephalin, Ala(2)-MePhe(4)-Gly(5)- promotes the reaction [CACNA1D protein results in increased transport of Barium]"11435619
D000643Ammonium ChlorideAmmonium Chloride affects the expression of CACNA1D mRNA16483693
D000661AmphetamineCACNA1D protein affects the reaction [Amphetamine results in increased expression of DRD2 mRNA alternative form]17026527
D000661AmphetamineCACNA1D protein affects the susceptibility to Amphetamine17026527
D000726Androgen Antagonists[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in increased expression of CACNA1D mRNA25607892
C015001arsenitearsenite results in decreased methylation of CACNA1D promoter23974009
D001464BariumCACNA1D protein results in increased transport of Barium11435619
D001464BariumCalcium inhibits the reaction [CACNA1D protein results in increased transport of Barium]11435619
D001464Barium"Enkephalin, Ala(2)-MePhe(4)-Gly(5)- promotes the reaction [CACNA1D protein results in increased transport of Barium]"11435619
D001464BariumIsradipine inhibits the reaction [CACNA1D protein results in increased transport of Barium]11435619
D001464BariumCACNA1D protein affects the transport of Barium15357422
D001464BariumCACNA2D2 gene mutant form inhibits the reaction [CACNA1D protein results in increased import of Barium]27798183
D001464BariumCACNA1D protein results in increased transport of Barium17567805
C044946benazeprilbenazepril inhibits the reaction [Thyroxine results in decreased expression of CACNA1D mRNA]21545815
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased expression of CACNA1D mRNA22316170
D004958Estradiol[Estradiol co-treated with Tetrachlorodibenzodioxin] results in increased expression of CACNA1D mRNA19619570
D004958EstradiolEstradiol results in increased expression of CACNA1D mRNA19619570
D004958EstradiolEstradiol results in decreased expression of CACNA1D mRNA19484750
D004958Estradiol[bisphenol A co-treated with Estradiol] results in decreased expression of CACNA1D mRNA26496021
D004958EstradiolEstradiol results in decreased expression of CACNA1D mRNA26945725
C006780bisphenol A[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in increased expression of CACNA1D mRNA25607892
C006780bisphenol A[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in increased expression of CACNA1D mRNA25607892
C006780bisphenol A[bisphenol A co-treated with Estradiol] results in decreased expression of CACNA1D mRNA26496021
C006780bisphenol A[bisphenol A co-treated with Testosterone] results in increased expression of CACNA1D mRNA26496021
C006780bisphenol Abisphenol A results in decreased expression of CACNA1D mRNA25181051
C006780bisphenol Abisphenol A results in increased methylation of CACNA1D gene28505145
C038091butylparaben[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in increased expression of CACNA1D mRNA25607892
C038091butylparaben[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in increased expression of CACNA1D mRNA25607892
C018475butyraldehydebutyraldehyde results in decreased expression of CACNA1D mRNA26079696
D019256Cadmium ChlorideCadmium Chloride results in increased expression of CACNA1D mRNA18308070
D002118CalciumCalcium inhibits the reaction [CACNA1D protein results in increased transport of Barium]11435619
D002118CalciumCACNA1D protein affects the transport of Calcium15357422
D002118CalciumCACNA2D2 gene mutant form inhibits the reaction [CACNA1D protein results in increased import of Calcium]27798183
D002118Calcium[CACNA1D protein co-treated with CACNB3 protein] results in increased transport of Calcium19796812
D002118Calcium[CACNA1D protein results in increased uptake of Calcium] which affects the localization of SLC2A2 protein17272349
D002118Calcium[CACNA1D protein results in increased uptake of Calcium] which results in increased phosphorylation of MYL9 protein17272349
D002118CalciumCACNA2D1 protein promotes the reaction [[CACNA1D protein co-treated with CACNB3 protein] results in increased transport of Calcium]19796812
D002118Calciumgabapentin affects the reaction [[CACNA1D protein co-treated with CACNB3 protein] results in increased transport of Calcium]19796812
D002118CalciumSLC5A1 protein affects the reaction [CACNA1D protein results in increased uptake of Calcium]17272349
D020111Chlorodiphenyl (54% Chlorine)Chlorodiphenyl (54% Chlorine) results in increased expression of CACNA1D mRNA21472459
D020111Chlorodiphenyl (54% Chlorine)Quercetin inhibits the reaction [Chlorodiphenyl (54% Chlorine) results in increased expression of CACNA1D mRNA]21472459
D002737ChloropreneChloroprene results in decreased expression of CACNA1D mRNA23125180
C018021cobaltous chloridecobaltous chloride results in decreased expression of CACNA1D mRNA24386269
D003042CocaineCACNA1D polymorphism affects the susceptibility to Cocaine28194001
C007262deoxynivalenoldeoxynivalenol results in increased expression of CACNA1D mRNA23792671
D003993Dibutyl Phthalate[Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of CACNA1D mRNA25607892
D002945Cisplatin[Cisplatin co-treated with jinfukang] results in decreased expression of CACNA1D mRNA27392435
D002945CisplatinCisplatin results in decreased expression of CACNA1D mRNA27392435
D003633Dichlorodiphenyl Dichloroethylene[Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of CACNA1D mRNA25607892
D004041Dietary FatsDietary Fats results in increased expression of CACNA1D mRNA25016146
D004051Diethylhexyl Phthalate[Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of CACNA1D mRNA25607892
D004147DioxinsDioxins affects the expression of CACNA1D mRNA20463971
C038939enzacamene[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in increased expression of CACNA1D mRNA25607892
C038939enzacamene[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in increased expression of CACNA1D mRNA25607892
C109476epoxiconazole[Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of CACNA1D mRNA25607892
D004997Ethinyl EstradiolEthinyl Estradiol results in decreased expression of CACNA1D mRNA15834898|1735126
D005620Freund's AdjuvantFreund's Adjuvant results in increased expression of CACNA1D mRNA20846436
C069837fullerene C60fullerene C60 results in decreased expression of CACNA1D mRNA19167457
C040029gabapentinCACNA2D1 protein results in increased susceptibility to [gabapentin affects the activity of [CACNA1D protein co-treated with CACNB3 protein]]19796812
C040029gabapentingabapentin affects the activity of [CACNA1D protein co-treated with CACNB3 protein]19796812
C040029gabapentingabapentin affects the reaction [[CACNA1D protein co-treated with CACNB3 protein] results in increased transport of Calcium]19796812
D005947Glucose[INS protein co-treated with Glucose] results in increased expression of CACNA1D mRNA22634610
C081309irbesartanirbesartan inhibits the reaction [Thyroxine results in decreased expression of CACNA1D mRNA]21545815
D017275IsradipineIsradipine inhibits the reaction [CACNA1D protein results in increased transport of Barium]11435619
C544151jinfukang[Cisplatin co-treated with jinfukang] results in decreased expression of CACNA1D mRNA27392435
D007657Ketone BodiesKetone Bodies results in decreased expression of CACNA1D mRNA16807920
D008044Linuron[Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of CACNA1D mRNA25607892
D008687MetforminMetformin results in decreased expression of CACNA1D mRNA25596134
D018817N-Methyl-3,4-methylenedioxyamphetamine"N-Methyl-3,4-methylenedioxyamphetamine results in increased expression of CACNA1D mRNA"20188158
D0150581-Naphthylisothiocyanate1-Naphthylisothiocyanate results in increased expression of CACNA1D mRNA12832660
D009532NickelNickel results in decreased expression of CACNA1D mRNA24768652
C028007nickel monoxidenickel monoxide results in decreased expression of CACNA1D mRNA19167457
D009538NicotineNicotine results in increased expression of CACNA1D protein11756415
D009543NifedipineNifedipine binds to and results in decreased activity of CACNA1D protein18441296
C007350nitrofennitrofen results in decreased expression of CACNA1D mRNA20638522
C118580octylmethoxycinnamate[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in increased expression of CACNA1D mRNA25607892
C118580octylmethoxycinnamate[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in increased expression of CACNA1D mRNA25607892
C101814perfluoro-n-undecanoic acidperfluoro-n-undecanoic acid results in decreased expression of CACNA1D mRNA23602845
C023036perfluorooctanoic acidperfluorooctanoic acid results in decreased expression of CACNA1D mRNA19162173
D010575PesticidesPesticides results in decreased methylation of CACNA1D gene28396702
D010634PhenobarbitalPhenobarbital results in increased expression of CACNA1D mRNA12832660
D010862PilocarpinePilocarpine results in decreased expression of CACNA1D protein17265461
D010862PilocarpinePilocarpine results in increased expression of CACNA1D protein17265461
C006253pirinixic acidpirinixic acid results in increased expression of CACNA1D mRNA12832660
D011285Pregnenolone CarbonitrilePregnenolone Carbonitrile results in increased expression of CACNA1D mRNA22698814
C045362prochloraz[Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of CACNA1D mRNA25607892
C035988procymidone[Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of CACNA1D mRNA25607892
D011374ProgesteroneProgesterone results in increased expression of CACNA1D mRNA22238285
D011794QuercetinQuercetin inhibits the reaction [Chlorodiphenyl (54% Chlorine) results in increased expression of CACNA1D mRNA]21472459
D012601Scopolamine HydrobromideScopolamine Hydrobromide results in increased expression of CACNA1D mRNA12818353
D012822Silicon DioxideSilicon Dioxide analog results in decreased expression of CACNA1D mRNA25895662
C017947sodium arsenitesodium arsenite affects the expression of CACNA1D mRNA29319823
C016104sodium bichromatesodium bichromate affects the expression of CACNA1D mRNA22110744
C016104sodium bichromatesodium bichromate results in decreased expression of CACNA1D mRNA25993096
D013739Testosterone[bisphenol A co-treated with Testosterone] results in increased expression of CACNA1D mRNA26496021
D013749Tetrachlorodibenzodioxin[Estradiol co-treated with Tetrachlorodibenzodioxin] results in increased expression of CACNA1D mRNA19619570
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of CACNA1D mRNA19619570|2290382
D013974Thyroxinebenazepril inhibits the reaction [Thyroxine results in decreased expression of CACNA1D mRNA]21545815
D013974Thyroxineirbesartan inhibits the reaction [Thyroxine results in decreased expression of CACNA1D mRNA]21545815
D013974ThyroxineThyroxine results in decreased expression of CACNA1D mRNA21545815
D014028Tobacco Smoke PollutionTobacco Smoke Pollution results in increased methylation of CACNA1D gene26756918
D014212TretinoinTretinoin results in increased expression of CACNA1D mRNA21934132
C015559trimellitic anhydridetrimellitic anhydride results in decreased expression of CACNA1D mRNA19042947
C013320tris(2-butoxyethyl) phosphatetris(2-butoxyethyl) phosphate affects the expression of CACNA1D mRNA29024780
D014635Valproic AcidValproic Acid results in increased expression of CACNA1D mRNA28001369
D014635Valproic AcidValproic Acid results in increased methylation of CACNA1D gene29154799
D001335Vehicle EmissionsVehicle Emissions results in increased methylation of CACNA1D gene25560391
C025643vinclozolin[Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of CACNA1D mRNA25607892
C025643vinclozolinvinclozolin results in increased expression of CACNA1D mRNA23034163

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0005245voltage-gated calcium channel activity-IBA21873635  
GO:0005245voltage-gated calcium channel activity-IDA11160515  21131953  
GO:0005245voltage-gated calcium channel activity-TAS-  
GO:0005262calcium channel activity-IMP25620733  28472301  
GO:0008331high voltage-gated calcium channel activity-IBA21873635  
GO:0008331high voltage-gated calcium channel activitycontributes_toIDA1309651  
GO:0030506ankyrin binding-ISS21859974  
GO:0046872metal ion binding-IEA-  
GO:0051393alpha-actinin binding-IPI17110593  
GO:0086007voltage-gated calcium channel activity involved in cardiac muscle cell action potential-IC21859974  
GO:0086059voltage-gated calcium channel activity involved SA node cell action potential-IMP21131953  
GO ID GO Term Qualifier Evidence PubMed
GO:0006816calcium ion transport-IBA21873635  
GO:0006816calcium ion transport-IDA11160515  
GO:0007188adenylate cyclase-modulating G-protein coupled receptor signaling pathway-ISS-  
GO:0007605sensory perception of sound-IMP21131953  
GO:0050796regulation of insulin secretion-TAS-  
GO:0051928positive regulation of calcium ion transport-IDA1309651  
GO:0060372regulation of atrial cardiac muscle cell membrane repolarization-ISS-  
GO:0070509calcium ion import-IBA21873635  
GO:0070509calcium ion import-IDA1309651  
GO:0070588calcium ion transmembrane transport-ISS-  
GO:0086002cardiac muscle cell action potential involved in contraction-IMP21131953  
GO:0086012membrane depolarization during cardiac muscle cell action potential-IC21859974  
GO:0086046membrane depolarization during SA node cell action potential-IMP21131953  
GO:0086091regulation of heart rate by cardiac conduction-IMP21131953  
GO:1901016regulation of potassium ion transmembrane transporter activity-ISS-  
GO:1901379regulation of potassium ion transmembrane transport-ISS-  
GO ID GO Term Qualifier Evidence PubMed
GO:0005886plasma membrane-ISS21859974  
GO:0005886plasma membrane-TAS-  
GO:0005891voltage-gated calcium channel complex-IDA11160515  
GO:0030018Z disc-ISS-  
GO:1990454L-type voltage-gated calcium channel complex-IDA1309651  
KEGG ID KEGG Term
hsa04010MAPK signaling pathway
hsa04020Calcium signaling pathway
hsa04260Cardiac muscle contraction
hsa04270Vascular smooth muscle contraction
hsa04912GnRH signaling pathway
hsa04930Type II diabetes mellitus
hsa04973Carbohydrate digestion and absorption
hsa05010Alzheimer's disease
hsa05410Hypertrophic cardiomyopathy (HCM)
hsa05412Arrhythmogenic right ventricular cardiomyopathy (ARVC)
hsa05414Dilated cardiomyopathy
Reactome ID Reactome Term Evidence
R-HSA-1266738Developmental BiologyIEA
R-HSA-1430728MetabolismTAS
R-HSA-1430728MetabolismIEA
R-HSA-163685Integration of energy metabolismTAS
R-HSA-163685Integration of energy metabolismIEA
R-HSA-375165NCAM signaling for neurite out-growthIEA
R-HSA-397014Muscle contractionTAS
R-HSA-400042Adrenaline,noradrenaline inhibits insulin secretionIEA
R-HSA-419037NCAM1 interactionsIEA
R-HSA-422356Regulation of insulin secretionTAS
R-HSA-422356Regulation of insulin secretionIEA
R-HSA-422475Axon guidanceIEA
R-HSA-5576891Cardiac conductionTAS
R-HSA-5576892Phase 0 - rapid depolarisationTAS
R-HSA-5576893Phase 2 - plateau phaseTAS

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal
24884436Chronic alcohol consumption from adolescence-to-adulthood in mice--hypothalamic gene expression changes in the dilated cardiomyopathy signaling pathway. (2014 May 9)Zou HBMC Neurosci
28497380From Gene to Behavior: L-Type Calcium Channel Mechanisms Underlying Neuropsychiatric Symptoms. (2017 Jul)Kabir ZDNeurotherapeutics
28194001Enhancing VTA Cav1.3 L-type Ca(2+) channel activity promotes cocaine and mood-related behaviors via overlapping AMPA receptor mechanisms in the nucleus accumbens. (2017 Dec)Martinez-Rivera AMol Psychiatry
27905406Differential Roles for L-Type Calcium Channel Subtypes in Alcohol Dependence. (2017 Apr)Uhrig SNeuropsychopharmacology