Gene: CAMKMT

79823
C2orf34|CLNMT|CaM KMT|Cam|KMT
calmodulin-lysine N-methyltransferase
protein-coding
2p21
Ensembl:ENSG00000143919 MIM:609559 Vega:OTTHUMG00000128761 UniprotKB:Q7Z624
NG_032944.1
SNP Mapped
1   ANCO-SNPs
AD
0   
NA (AD)  NA (ND)   (Frontal_Cortex)
8.713e-1 (AD)  7.059e-1 (ND)

ANCO-SNPs

SNP ID Position Alleles Trait Variation Type
rs1067344chr2:44393671 (GRCh38.p7)T>Galcohol dependenceSNV(Single Nucleotide Variation)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
SNTA10.851
IQCK0.831
PBXIP10.816
SELENBP10.809
METTL7A0.809
NTSR20.807
PPP1R1B0.805
FXYD10.802
IL17D0.789
TNFSF130.789

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
OR4F5-0.48
OR4F29-0.431
CCDC68-0.387
IGSF10-0.376
SCARA5-0.375
ARNTL2-0.369
SOGA3-0.368
CLMP-0.364
CD163L1-0.36
SRGAP2C-0.359

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
C4591794-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of CAMKMT mRNA"27188386
C516138(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of CAMKMT mRNA"27188386
D018501Antirheumatic AgentsAntirheumatic Agents results in increased expression of CAMKMT mRNA24449571
D001280AtrazineAtrazine results in increased expression of CAMKMT mRNA22378314
D001564Benzo(a)pyreneBenzo(a)pyrene results in decreased expression of CAMKMT mRNA20106945|2163298
C006780bisphenol Abisphenol A results in decreased expression of CAMKMT mRNA25181051
D019256Cadmium ChlorideCadmium Chloride results in decreased methylation of CAMKMT promoter22457795
C018021cobaltous chloridecobaltous chloride results in decreased expression of CAMKMT mRNA24386269
D002945Cisplatin[Cisplatin co-treated with jinfukang] results in decreased expression of CAMKMT mRNA27392435
D002945CisplatinCisplatin results in decreased expression of CAMKMT mRNA22023808
C045651epigallocatechin gallate[potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of CAMKMT mRNA22079256
D005020Ethyl MethanesulfonateEthyl Methanesulfonate results in decreased expression of CAMKMT mRNA23649840
D005557FormaldehydeFormaldehyde results in decreased expression of CAMKMT mRNA23649840
C039281furanfuran results in increased expression of CAMKMT mRNA25539665
C039281furanfuran results in increased methylation of CAMKMT gene22079235
D017313FenretinideFenretinide results in decreased expression of CAMKMT mRNA28973697
C544151jinfukang[Cisplatin co-treated with jinfukang] results in decreased expression of CAMKMT mRNA27392435
D008741Methyl MethanesulfonateMethyl Methanesulfonate results in decreased expression of CAMKMT mRNA23649840
C406082monomethylarsonous acidmonomethylarsonous acid results in decreased expression of CAMKMT protein24625837
D010662Phenylmercuric Acetate"[NOG protein co-treated with Phenylmercuric Acetate co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of CAMKMT mRNA"27188386
D010662Phenylmercuric AcetatePhenylmercuric Acetate results in decreased expression of CAMKMT mRNA26272509
C027373potassium chromate(VI)[potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of CAMKMT mRNA22079256
C027373potassium chromate(VI)potassium chromate(VI) results in decreased expression of CAMKMT mRNA22079256
D011794QuercetinQuercetin results in decreased expression of CAMKMT mRNA21632981
C004648testosterone enanthatetestosterone enanthate affects the expression of CAMKMT mRNA17440010
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the expression of CAMKMT mRNA22298810
D013853ThioacetamideThioacetamide results in increased expression of CAMKMT mRNA23411599
D014212TretinoinTretinoin results in decreased expression of CAMKMT mRNA21934132
C012589trichostatin Atrichostatin A results in increased expression of CAMKMT mRNA15901671
D014635Valproic AcidValproic Acid affects the expression of CAMKMT mRNA25979313
D014635Valproic AcidValproic Acid results in increased expression of CAMKMT mRNA23179753|2718838
D014635Valproic AcidValproic Acid results in increased expression of CAMKMT mRNA15901671

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0018025calmodulin-lysine N-methyltransferase activity-IBA21873635  
GO:0018025calmodulin-lysine N-methyltransferase activity-TAS-  
GO:0031072heat shock protein binding-IPI23349634  
GO ID GO Term Qualifier Evidence PubMed
GO:0006479protein methylation-TAS-  
GO:0007005mitochondrion organization-IEA-  
GO:0018022peptidyl-lysine methylation-IEA-  
GO:0022400regulation of rhodopsin mediated signaling pathway-TAS-  
GO ID GO Term Qualifier Evidence PubMed
GO:0005634nucleus-IDA-  
GO:0005737cytoplasm-IDA23349634  
GO:0005794Golgi apparatus-IEA-  
GO:0005829cytosol-TAS-  
GO:0032991protein-containing complex-IDA23349634  
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence
R-HSA-162582Signal TransductionTAS
R-HSA-2187338Visual phototransductionTAS
R-HSA-2514856The phototransduction cascadeTAS
R-HSA-2514859Inactivation, recovery and regulation of the phototransduction cascadeTAS
R-HSA-372790Signaling by GPCRTAS
R-HSA-388396GPCR downstream signallingTAS
R-HSA-392499Metabolism of proteinsTAS
R-HSA-418594G alpha (i) signalling eventsTAS
R-HSA-597592Post-translational protein modificationTAS
R-HSA-8876725Protein methylationTAS

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal