Gene: LRMDA

83938
C10orf11|CDA017
leucine rich melanocyte differentiation associated
protein-coding
10q22.2-q22.3
Ensembl:ENSG00000148655 MIM:614537 Vega:OTTHUMG00000018532 UniprotKB:Q9H2I8
NG_042180.1
SNP Mapped
1   ANCO-SNPs
AD
0   
NA (AD)  NA (ND)   (Frontal_Cortex)
8.002e-1 (AD)  9.093e-1 (ND)

ANCO-SNPs

SNP ID Position Alleles Trait Variation Type
rs10762705chr10:76268705 (GRCh38.p7)G>Aalcohol dependenceSNV(Single Nucleotide Variation)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
D000082AcetaminophenAcetaminophen results in decreased expression of LRMDA mRNA29067470
D016604Aflatoxin B1Aflatoxin B1 affects the expression of LRMDA protein20106945
D016604Aflatoxin B1Aflatoxin B1 results in decreased expression of LRMDA mRNA21641981|2210060
D016604Aflatoxin B1Aflatoxin B1 results in increased methylation of LRMDA gene27153756
D001151ArsenicArsenic affects the methylation of LRMDA gene25304211
D001564Benzo(a)pyreneBenzo(a)pyrene results in decreased expression of LRMDA mRNA20064835|2010694
D0151237,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide"7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of LRMDA mRNA"26238291
C006780bisphenol Abisphenol A results in increased expression of LRMDA mRNA25181051
C006780bisphenol Abisphenol A results in increased methylation of LRMDA gene28505145
D019327Copper SulfateCopper Sulfate results in decreased expression of LRMDA mRNA19549813
D016572CyclosporineCyclosporine results in decreased expression of LRMDA mRNA25562108
D002945CisplatinCisplatin results in decreased expression of LRMDA mRNA27594783
D004147DioxinsDioxins affects the expression of LRMDA mRNA20463971
C118739entinostatentinostat results in increased expression of LRMDA mRNA27188386
D017313FenretinideFenretinide results in decreased expression of LRMDA mRNA28973697
D008741Methyl MethanesulfonateMethyl Methanesulfonate results in decreased expression of LRMDA mRNA26011545
D009151Mustard GasMustard Gas results in decreased expression of LRMDA mRNA25102026
D017035PravastatinPravastatin results in decreased expression of LRMDA mRNA27225895
D011794QuercetinQuercetin results in decreased expression of LRMDA mRNA21632981
D012822Silicon DioxideSilicon Dioxide analog results in decreased expression of LRMDA mRNA25895662
C075117squalestatin 1squalestatin 1 results in increased expression of LRMDA mRNA27225895
C075117squalestatin 1squalestatin 1 results in increased expression of LRMDA mRNA27225895
C016805tris(1,3-dichloro-2-propyl)phosphate"tris(1,3-dichloro-2-propyl)phosphate results in increased expression of LRMDA mRNA"26179874
D014635Valproic AcidValproic Acid affects the expression of LRMDA mRNA25979313
D014635Valproic AcidValproic Acid results in decreased expression of LRMDA mRNA29154799
D014635Valproic AcidValproic Acid results in increased expression of LRMDA mRNA23179753|2438349
C111237vorinostatvorinostat results in increased expression of LRMDA mRNA27188386
D019287Zinc SulfateZinc Sulfate results in decreased expression of LRMDA mRNA27504894

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO ID GO Term Qualifier Evidence PubMed
GO:0030318melanocyte differentiation-IBA21873635  
GO:0030318melanocyte differentiation-IMP23395477  
GO ID GO Term Qualifier Evidence PubMed
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal