Gene: MINDY4

84182
C7orf67|FAM188B
MINDY lysine 48 deubiquitinase 4
protein-coding
7p14.3
Ensembl:ENSG00000106125 Vega:OTTHUMG00000152800 UniprotKB:Q4G0A6
NC_000007.14
SNP Mapped
2   ANCO-SNPs
ND|AD
0   
NA (AD)  NA (ND)   (Frontal_Cortex)
6.947e-1 (AD)  6.191e-1 (ND)

ANCO-SNPs

SNP ID Position Alleles Trait Variation Type
rs10229281chr7:30837026 (GRCh38.p7)G>Anicotine dependenceSNV(Single Nucleotide Variation)
rs11765514chr7:30781314 (GRCh38.p7)G>Talcohol dependenceSNV(Single Nucleotide Variation)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
C0297902,2',3',4,4',5-hexachlorobiphenyl"2,2',3',4,4',5-hexachlorobiphenyl results in decreased expression of MINDY4 mRNA"23829299
D020106AcrylamideAcrylamide results in decreased expression of MINDY4 mRNA28959563
D016604Aflatoxin B1Aflatoxin B1 results in increased methylation of MINDY4 gene27153756
D018501Antirheumatic AgentsAntirheumatic Agents results in increased expression of MINDY4 mRNA24449571
D001151ArsenicArsenic affects the methylation of MINDY4 gene25304211
C006780bisphenol Abisphenol A results in decreased expression of MINDY4 mRNA25181051
D003471CuprizoneCuprizone results in increased expression of MINDY4 mRNA26577399
D003561CytarabineCytarabine results in decreased expression of MINDY4 mRNA21198554
D003999Dichloroacetic AcidDichloroacetic Acid results in increased expression of MINDY4 mRNA28962523
C412815GW 4064GW 4064 results in increased expression of MINDY4 mRNA26655953
C016517indole-3-carbinolindole-3-carbinol affects the expression of MINDY4 mRNA21396975
D018817N-Methyl-3,4-methylenedioxyamphetamine"N-Methyl-3,4-methylenedioxyamphetamine results in increased expression of MINDY4 mRNA"20188158
D012822Silicon DioxideSilicon Dioxide analog results in increased expression of MINDY4 mRNA25895662
D012834SilverSilver affects the expression of MINDY4 mRNA27131904
D013853ThioacetamideThioacetamide results in increased expression of MINDY4 mRNA23411599
D014212TretinoinTretinoin results in decreased expression of MINDY4 mRNA23724009
D001335Vehicle EmissionsVehicle Emissions results in increased methylation of MINDY4 gene25560391

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0036459thiol-dependent ubiquitinyl hydrolase activity-IEA-  
GO ID GO Term Qualifier Evidence PubMed
GO:0006508proteolysis-IEA-  
GO ID GO Term Qualifier Evidence PubMed
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal